A Meta-Analysis of the Use of Nonsteroidal Antiinflammatory Drugs for Pediatric Postoperative Pain

Oral morphine versus ibuprofen administered at home for postoperative orthopedic pain in children: a randomized controlled trial

“…49 Unlike patients receiving care in hospital, our sample included children who underwent minor surgeries that may not have been associated with severe pain 43 and who may have experienced less distress in their home environment. Among pediatric inpatients, anxiety has been found to be highly correlated with postoperative pain.…”

Postoperative nonsteroidal anti-inflammatory drugs and risk of bleeding in pediatric intracapsular tonsillectomy

“…Nonsteroidal anti-inflammatory drugs (NSAID), specifically ibuprofen, have gained favor as an alternative to narcotics for postoperative pain control. While NSAIDs provide adequate post-tonsillectomy analgesia, 4 their routine use remains controversial as NSAIDs also cause platelet dysfunction that may lead to increased risk of posttonsillectomy hemorrhage (PTH). The clinical impact of this potentially increased bleeding risk with NSAID use remains unclear.…”

Effect of Pre-Emptive Paracetamol Infusion on Postoperative Analgesic Consumption in Children Undergoing Elective Herniorrhaphy

“…The addition of paracetamol or nonsteroidal anti-inflammatory drugs (NSAIDs) may decrease opioid requirement (13-15). Michelet et al (16) in their meta-analysis have shown that perioperative administration of NSAIDs reduces opioid consumption, nausea and vomiting during the postoperative period in children.…”