Because of the 15%-30% prevalences of white-coat blood pressure (BP) elevation 1 and masked hypertension, 2 out-of-office BP measurement is recommended to confirm the diagnosis of hypertension for most patients using either 24-hour ambulatory or home BP monitoring. [3][4][5][6][7][8] Still, accurate office BP measurement (OBPM) remains essential to limit the need for labor-intensive and expensive out-of-office BP monitoring. Unfortunately, OBPM in routine clinical practice is often performed inaccurately due to incorrect patient preparation and manual auscultatory measurement technique. 9,10 To improve OBPM accuracy, current guidelines recommend validated, automatic oscillometric devices to replace manual auscultatory BP measurement. 3-7 But guideline-recommended OBPM with these devices does not eliminate white-coat BP elevation. 10,11 In contrast, validated, automated oscillometric devices that automatically perform and average three to five BP measurements over 3-5 minutes while the patient rests alone in the exam room or another quiet place have been demonstrated to substantially reduce white-coat BP elevation. 12,13 This approach to OBPM, termed unattended automated office BP measurement (u-AOBP), is recommended as the preferred OBPM technique for patients with an initial elevated observed BP measurement by the Abstract Unattended automated office blood pressure (BP) measurement (u-AOBP) improves office BP measurement accuracy and reduces white-coat BP elevation, but there are reservations about its time efficiency in primary care. We used time-stamp methodology to measure u-AOBP procedure times performed without a rest period in 130 patients during routine clinic visits to three primary care clinics with 2.5-4.9 years u-AOBP experience. We documented the clinical activities of 30 medical assistants during the u-AOBP procedures. We also assessed MA and clinician satisfaction and knowledge about u-AOBP performance and interpretation. Median u-AOBP procedure time was <5 minutes, and MAs engaged in productive clinical activities during 83% of the procedures. Ninety-three percent of MAs and 100% of clinicians in the clinics agreed that u-AOBP is an efficient method to improve hypertension management. Barriers to effective u-AOBP implementation and ongoing utilization included initial difficulty incorporating u-AOBP into clinic workflow and medical staff knowledge deficiencies concerning correct u-AOBP performance and interpretation despite prior training and experience with the procedure. Intensive u-AOBP education and training programs are needed to facilitate effective u-AOBP implementation into primary care. The time required to perform u-AOBP can be utilized productively by staff.