A Meta-analytic Review of the Psychosocial Adjustment of Youth with Inflammatory Bowel Disease

Abstract

Clinical attention to depressive disorders, QOL, and social functioning may be particularly salient in the context of pediatric IBD.

Increased Risks of Developing Anxiety and Depression in Young Patients With Crohn's Disease

“…In addition to the burden carried by adult patients, short stature and delayed puberty can also contribute to appearing and feeling diff erent from peers, which may increase the psychologic burden of IBD in young patients ( 23 ). A recent meta-analytic review indicated that pediatric patients with IBD demonstrated elevations in certain psychosocial domains, including parentreported internalizing symptoms, compared with healthy controls ( 24 ). Measures of depressive and anxiety symptoms relying primarily on youth report of symptoms did not reveal diff erences between youth with IBD and either healthy controls or children with other chronic illnesses, but children with IBD were found to be at higher risk for depressive disorders compared with youth with other chronic illnesses ( 24 ).…”

“…A recent meta-analytic review indicated that pediatric patients with IBD demonstrated elevations in certain psychosocial domains, including parentreported internalizing symptoms, compared with healthy controls ( 24 ). Measures of depressive and anxiety symptoms relying primarily on youth report of symptoms did not reveal diff erences between youth with IBD and either healthy controls or children with other chronic illnesses, but children with IBD were found to be at higher risk for depressive disorders compared with youth with other chronic illnesses ( 24 ). Szigethy et al ( 25 ) conducted a study of 102 patients aged 11 -17 years with IBD, and estimated that 24.5 % had clinically meaningful symptoms of depression.…”

“…Some patients may have to limit their social activities to those with a bathroom nearby, or patients may unexpectedly cancel planned activities owing to disease fl ares. In children and adolescents, the symptoms and nature of CD might explain a higher risk for mental health disorders, including body image issues related to delayed growth and puberty, embarrassment, and isolation; perceived loss of control; and limited ability to participate in sports and school activities ( 23,24,35 ). Engstrom ( 36 ) found that psychiatric disorders and behavior problems were more common for children with IBD than for healthy children and children with diabetes or tension headache and that depression, anxiety, and low self-esteem were common in children with IBD.…”

Depression in Autoimmune Diseases

“…We will concentrate on systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA), since in these diseases large cohort studies on mental health have been conducted and therefore a relatively amount of data are available. However, depression-like symptoms have also been well described in many other autoimmune diseases including multiple sclerosis and inflammatory bowel disease (for review see (Greenley et al, 2010;Marrie et al, 2015)). Moreover, depression-like symptoms are also a hallmark of autoinflammatory diseases.…”

Letter: risk factors and impacts of psychological morbidity in young people with inflammatory bowel disease

“…From this perspective, the results and conclusions may be not as strong as the previous reviews. 4,5 We agree that an individual's psychological adjustment to illness is influenced by disease severity and illness perceptions. In addition, an inter-relationship between IBD activity, IBD perceptions, coping strategies and depression exists.…”