A method for measuring locomotor behavior in rodents: Contrast-sensitive computer-controlled video tracking activity assessment in rats

Vorhees, Charles V.; Acuff‐Smith, Karen D.; Minck, Daniel R.; Butcher, Richard E.

doi:10.1016/0892-0362(92)90027-8

Cited by 50 publications

(23 citation statements)

References 4 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The image was analyzed using a San Diego Instruments contrast-sensitive video tracking analyzer (see Vorhees et al 1992). The tracker software divided the compartment into four corner squares, four side sections between the corners (rectangular) and one central square.…”

Section: Methodsmentioning

confidence: 99%

Methamphetamine exposure during early postnatal development in rats: II. Hypoactivity and altered responses to pharmacological challenge

et al. 1994

View full text Add to dashboard Cite

Methamphetamine induces neurotransmitter reductions and neurotoxicity at high doses in adult animals, but its effects on early brain development and behavior have received little attention. In this experiment the effects of methamphetamine exposure during a period equivalent to the human third trimester were examined. Rats (Sprague-Dawley CD) were injected subcutaneously with d-methamphetamine (d-MA) (30 mg/kg b.i.d.) early in postnatal development (days 1-10), later (postnatal days 11-20), or with water during both of these periods. Both early and later MA-exposed offspring exhibited reduced locomotor activity. The effect was most evident at 30 days of age and was smaller at 45 and 60 days and only present at these latter ages in males. Only the early MA exposure group showed prolonged suppression of activity in response to a challenge dose of fluoxetine and a persistent deficit in weight while only the later MA exposure group showed attenuated suppression of activity in response to a challenge dose of fluoxetine. Based both on the present data and those in the preceding article, it was concluded that the effects of MA are both long lasting and stage dependent and involve arousal as well as cognitive functions.

show abstract

Section: Methodsmentioning

confidence: 99%

Methamphetamine exposure during early postnatal development in rats: II. Hypoactivity and altered responses to pharmacological challenge

et al. 1994

View full text Add to dashboard Cite

show abstract

“…Another early method, still used in some commercially available systems, is to feed the analog video signal to a dedicated video tracking unit, which detects peaks in the voltage of the video signal (indicating a region of high contrast between the tracked animal and the background), and use this to produce the x,y coordinates of the tracked animals. This output is then fed to the serial port of a computer (Klapdor, Dulfer, & van der Staay, 1996;Vorhees, Acuff-Smith, Minck, & Butcher, 1992). These analog systems have the disadvantage of being relatively inflexible (dedicated to particular experimental setups) and can normally track only one animal in rather restricted lighting and background conditions.…”

Section: Video Trackingmentioning

confidence: 99%

EthoVision: A versatile video tracking system for automation of behavioral experiments

Noldus

Spink

Tegelenbosch

2001

Behavior Research Methods, Instruments, & Computers

601

446

View full text Add to dashboard Cite

“…Another early method was to feed the analog video signal to a dedicated video tracking unit, which detected peaks in the voltage of the video signal (indicating a region of high contrast between the tracked animal and background), and used this to produce the x, y coordinates of the tracked animals as output which was then fed to the serial port of a computer [21,22]. These analog systems have the disadvantage of being relatively inflexible (dedicated to particular experimental setups) and can normally only track one animal, in rather restricted lighting and background conditions.…”

Section: The Development Of Automated Observation Systemsmentioning

confidence: 99%

The EthoVision video tracking system—A tool for behavioral phenotyping of transgenic mice

Spink

Tegelenbosch

Buma

et al. 2001

Physiology & Behavior

236

164

View full text Add to dashboard Cite

A method for measuring locomotor behavior in rodents: Contrast-sensitive computer-controlled video tracking activity assessment in rats

Cited by 50 publications

References 4 publications

Methamphetamine exposure during early postnatal development in rats: II. Hypoactivity and altered responses to pharmacological challenge

Methamphetamine exposure during early postnatal development in rats: II. Hypoactivity and altered responses to pharmacological challenge

EthoVision: A versatile video tracking system for automation of behavioral experiments

The EthoVision video tracking system—A tool for behavioral phenotyping of transgenic mice

Contact Info

Product

Resources

About