This paper focuses on understanding the dynamic response problem of flexible wrapped reinforced Earth slope under the coupling effect of earthquake and rainfall; a numerical calculation model of reinforced Earth slope considering the coupling effect of earthquake and rainfall was established. The dynamic response, pore pressure, and tensile stress distribution of the reinforcement under the rainfall before earthquake, the rainfall after the earthquake, and earthquake-rainfall are studied. The results show that the coupling effect of earthquake and rainfall is an influential factor in the dynamic analysis of reinforced Earth slopes, the analysis of which should be paid attention to and researched in the future. The combination of geogrid and soil effectively improves the deformation of the slope and the overall stability, reduces the secondary disaster of the slope, and provides a reference for the seismic construction design of the reinforced Earth slope.