A method to obtain the same levels of CT image noise for patients of various sizes, to minimize radiation dose

Starck, Göran; Lönn, Lars; Cederblad, Åke; Forssell-Aronsson, Eva; Sjöström, Lars; Alpsten, M.

doi:10.1259/bjr.75.890.750140

Cited by 74 publications

(54 citation statements)

References 20 publications

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“…In this study, the dose efficacy concept was introduced and used at a level of 0.5 HU mGy −1 on the basis of results obtained from the Rose model observer. It appears that for the unit and slice thickness investigated this dose efficacy leads to an image noise level of about 10 HU for children weighing 839 [30], this corresponds to images of very good quality, since images with a standard deviation of 10 HU were considered of high quality whereas images with a standard deviation of 30 HU were considered very noisy. Thus, the dose levels proposed in this paper can be reduced when image quality requirements are not particularly high.…”

Section: Discussionmentioning

confidence: 98%

Management of patient dose and image noise in routine pediatric CT abdominal examinations

Verdun¹,

Lepori

Monnin³

et al. 2004

European Radiology

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The aim was to propose a strategy for finding reasonable compromises between image noise and dose as a function of patient weight. Weighted CT dose index (CTDI w ) was measured on a multidetector-row CT unit using CTDI test objects of 16, 24 and 32 cm in diameter at 80, 100, 120 and 140 kV. These test objects were then scanned in helical mode using a wide range of tube currents and voltages with a reconstructed slice thickness of 5 mm. For each set of acquisition parameter image noise was measured and the Rose model observer was used to test two strategies for proposing a reasonable compromise between dose and lowcontrast detection performance: (1) the use of a unique noise level for all test object diameters, and (2) the use of a unique dose efficacy level defined as the noise reduction per unit dose. Published data were used to define four weight classes and an acquisition protocol was proposed for each class. The protocols have been applied in clinical routine for more than one year. CTDI vol values of 6.7, 9.4, 15.9 and 24.5 mGy were proposed for the following weight classes: 2.5-5, 5-15, 15-30 and 30-50 kg with image noise levels in the range of 10-15 HU. The proposed method allows patient dose and image noise to be controlled in such a way that dose reduction does not impair the detection of low-contrast lesions. The proposed values correspond to highquality images and can be reduced if only high-contrast organs are assessed.

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Section: Discussionmentioning

confidence: 98%

Management of patient dose and image noise in routine pediatric CT abdominal examinations

Verdun¹,

Lepori

Monnin³

et al. 2004

European Radiology

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“…The tube voltage was 120 kV. Slice thickness and tube current were set according to a dose reduction scheme (15). Precision errors were calculated from double determinations: subcutaneous adipose tissue (0.5%) and the sum of intraperitoneal and retroperitoneal adipose tissue areas (intra-abdominal adipose tissue area; 1.2%).…”

Section: Methodsmentioning

confidence: 99%

Pubertal Timing Is an Independent Predictor of Central Adiposity in Young Adult Males

et al. 2006

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The role of puberty and normal variations in pubertal timing for the development of obesity in men is unclear. The aim of the current study was to investigate the impact of pubertal timing and prepubertal BMI (kg/m 2 ) for young adult BMI and fat mass distribution. Detailed growth charts from birth to age 18 -20 years were retrieved for the men participating in the population-based Gothenburg Osteoporosis and Obesity Determinants study. Age at peak height velocity (PHV) and BMI at age 10 years were estimated for 579 subjects, and PHV was used as an assessment of pubertal timing. The fat mass characterization and distribution were analyzed using dual X-ray absorptiometry and peripheral as well as abdominal computed tomography at age 18.9 ؎ 0.5 years. We demonstrate that age at PHV is an independent negative predictor of young adult BMI and whole-body fat mass. Interestingly, age at PHV is an independent negative predictor of central, but not peripheral, fat mass. In contrast, BMI at 10 years of age predicts both central and peripheral subcutaneous fat mass.In conclusion, we demonstrate that early pubertal onset specifically predicts a central fat mass distribution, while a predominantly subcutaneous obese phenotype is strongly predicted by a high prepubertal BMI. Diabetes 55: [3047][3048][3049][3050][3051][3052] 2006 O besity has grown into an epidemic in the Western world, and not only adults but also children are now treated for metabolic syndrome disorders. Obesity is an important risk factor for the development of diabetes and cardiovascular disease, and in the National Health and Nutrition Examination Survey, 12.6% of boys aged 8 -14 years were obese and 29.1% were overweight (1,2). Puberty has been identified as a critical period for the development of overweight (3), but the role of puberty and variations within the normal range in pubertal timing for the development of obesity in men are unknown. Age at pubertal onset is decreasing, and although girls are more extensively studied in this respect, there are reports of secular trends in pubertal onset for boys as well (4,5).Kaplowitz et al. (6) reported a negative association between prepubertal BMI (weight in kilograms divided by the square of height in meters) and the timing of puberty in female subjects. Furthermore, an association between early age at menarche and increased adult BMI has been reported (7,8), but the impact of pubertal timing independent of prepubertal BMI was not investigated in these studies (7,8). The independent predictive role of pubertal timing, adjusted for prepubertal BMI, for adult BMI in female subjects has recently been investigated in two longitudinal studies: the Newton Study and the Bogalusa Heart Study. In the Newton Study (9), pubertal timing did not predict adult BMI independently of prepubertal BMI, and from the Bogalusa Heart Study (10) it was concluded that after adjustment for prepubertal BMI, menarcheal age no longer predicts adult BMI. Thus, pubertal timing is a negative predictor of adult BMI, but, after adjust...

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“…Despite this, it has been recently shown that there is possibility to gather goodquality images with a decreased tube voltage by increasing iodine absorption when the heart is exposed to a lower voltage. [26][27][28] CONClUsION Cardiac computed tomography is reliable imaging method, which has grown rapidly in the last decade and continues to develop in order to achieve what patients and clinicians are looking for -the best decision-making process in terms of diagnosis. However, these improvements also bring side effects, which have to be managed judiciously by clinicians, radiology engineers, and manufacturers.…”

Section: Tube Voltagementioning

confidence: 99%

Actual Dose-Reduction Strategies in Cardiac Computed Tomography

Cernica¹,

Hodaş²,

Himcinschi³

et al. 2017

Journal of Interdisciplinary Medicine

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Computed tomography (CT) in cardiac examination is a powerful imaging tool that has developed rapidly during the last decade and continues to increase its potential by bringing novel technologies. Due to its noninvasive character, cardiac CT became a largely used method in detecting coronary diseases or functional issues at the expense of conventional coronary angiography. The accuracy of images has also increased, especially since new generation dual-source multi-slice detectors were developed. Although there are continuous improvements that serve to gain better-quality images, thus increasing their diagnostic accuracy, there is an inconvenient that became a serious topic for debate in the current literature: exposure to higher doses of radiation during cardiac CT examinations. Fortunately, physicians and manufacturers are taking into consideration the need to apply new strategies for radiation dose-reduction. Thus, this objective can be achieved by using patient-tailored dose-reduction strategies and by modulating the technical features of the CT scanners in order to gather highquality images with minimal radiation exposure. The aim of this manuscript was to review the current literature data on dose-reduction strategies that are used for cardiovascular computed tomography scans.

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A method to obtain the same levels of CT image noise for patients of various sizes, to minimize radiation dose

Cited by 74 publications

References 20 publications

Management of patient dose and image noise in routine pediatric CT abdominal examinations

Management of patient dose and image noise in routine pediatric CT abdominal examinations

Pubertal Timing Is an Independent Predictor of Central Adiposity in Young Adult Males

Actual Dose-Reduction Strategies in Cardiac Computed Tomography

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