A methodologic study of post-marketing drug evaluation using a pharmacy-based approach

Ec, Borden; Lee, John G.

doi:10.1016/0021-9681(82)90092-3

Cited by 37 publications

(8 citation statements)

References 4 publications

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“…The PMMP is a communitybased prospective medication surveillance program based at St Joseph's Hospital in Hamilton, Ontario that targets users of specific medication classes. The methods used to recruit pharmacies and enroll patients have been published elsewhere (13,14). The Bronchial Inhalers project received ethics approval from McMaster University, Hamilton, Ontario, and participants provided written informed consent.…”

Section: Methodsmentioning

confidence: 99%

The Patient Level Cost of Asthma in Adults in South Central Ontario

Ungar

Coyte²,

MacKeigan³

1998

Canadian Respiratory Journal

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Section: Methodsmentioning

confidence: 99%

The Patient Level Cost of Asthma in Adults in South Central Ontario

Ungar

Coyte²,

MacKeigan³

1998

Canadian Respiratory Journal

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“…The validity of event reporting was assessed by calculating its sensitivity and specificity when compared with the full telephone interview, which was taken as the standard." To test the agreement between the BMJ VOLUME 297 8 patients' and experts' perceptions of adverse reactions the experts evaluated all events elicited in the telephone interviews, judging each to be probably related to treatment or not. We then examined each patient's reaction report to determine which events the patient had identified as adverse reactions.…”

Section: Methodsmentioning

confidence: 99%

Patients as a direct source of information on adverse drug reactions.

Mitchell

Henry

Sanson‐Fisher

et al. 1988

BMJ

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“…The methods used to enroll patients have been published elsewhere (12,13). Patients filling inhaler prescriptions in community pharmacies in southern Ontario reported medication use, health services use, and symptoms through telephone interviews over a 6-mo period.…”

Section: Study Samplementioning

confidence: 99%

Assessment of a Medication-Based Asthma Index for Population Research

Ungar

Santos

2002

Am J Respir Crit Care Med

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Asthma management guidelines recommend the use of preventive medications in sufficient amounts to control asthma symptoms. The validity of a medication use index as a proxy for asthma severity has not been established. We recruited 1,279 Ontario adults with asthma or parents of children with asthma from a community-based surveillance program in 1995-96. Participants completed a telephone questionnaire at baseline, 3 and 6 mo. The questionnaire gathered information about asthma medication use, health care utilization, and symptoms. Asthma was classified as mild in 28%, moderate in 49%, or severe in 23% of patients based on the amount and types of medication used. There were significant differences among groups in health resource use such that adults with higher medication use visited primary care physicians and specialists more frequently, had pulmonary functions tests more frequently, and were admitted to hospital more frequently. The findings among children were similar. There were weak positive correlations between medication use and symptom frequency in adults and children. We conclude that a medication use index may be useful in population-based research where clinical asthma severity data are lacking. Such an index is distinct from but is related to disease control.

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A methodologic study of post-marketing drug evaluation using a pharmacy-based approach

Cited by 37 publications

References 4 publications

The Patient Level Cost of Asthma in Adults in South Central Ontario

The Patient Level Cost of Asthma in Adults in South Central Ontario

Patients as a direct source of information on adverse drug reactions.

Assessment of a Medication-Based Asthma Index for Population Research

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