2008
DOI: 10.1007/s10973-007-8851-8
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A microcalorimetric assay of tetrahymena thermophila for assessing tributyltin acute toxicity

Abstract: The power-time curves of Tetrahymena thermophila exposed to tributyltin (TBT) were detected by microcalorimetry. Metabolic rate (r) decreased significantly while peak time (PT) increased with the enhancement of TBT level. Compared with the measured multibiomarker including catalase, lactate dehydrogenase, glutathione S-transferase, ATPase and membrane fluidity, PT and r could be sensitive biomarkers for assessing TBT toxicity at cellular level. The effective concentrations obtained by them were consistent to t… Show more

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Cited by 13 publications
(2 citation statements)
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“…With the development of the microcalorimetry, it has been used widely to monitor the growth metabolism of many living organisms and applied in many fields, such as physiology, pharmacology, ecology, and environmental sciences [2][3][4][5][6][7].…”
Section: Introductionmentioning
confidence: 99%
See 1 more Smart Citation
“…With the development of the microcalorimetry, it has been used widely to monitor the growth metabolism of many living organisms and applied in many fields, such as physiology, pharmacology, ecology, and environmental sciences [2][3][4][5][6][7].…”
Section: Introductionmentioning
confidence: 99%
“…Besides, the growth metabolism of Tetrahymena has been studied by microcalorimetry [5,6]. The present study aims to record the heat production during the nongrowth metabolic processes of the different strains of Tetrahymena cells.…”
Section: Introductionmentioning
confidence: 99%