A new analytical method is proposed for the analysis of boundary effect in a pipe bend portion loaded by bending moment combined with internal pressure. The proposed method is based on the simplifying hypotheses, which make possible to represent all deformation-and force-related parameters in terms of the tangential displacement assumed in the form of the Fourier series expansion by the circumferential coordinate. A set of quadric differential equations by axial coordinate containing unknown displacement expansion coefficients is derived. We obtained an analytical approximate solution for a pipe bend portion and precise solution for a straight pipe, which are expressed via Krylov functions. We formulate the application procedure for the method of initial parameter, where the values of tangential and longitudinal displacements, axial and tangential forces are used as boundary conditions. We present the equations relating the above-mentioned parameters in the initial and end sections of the pipe bend portion. The results obtained are compared with the available published data.