The burden of disability and mortality from non-communicable diseases (NCDs) has increased worldwide. This rise in NCD cases is seen in the productive age group, and there is a growing trend among those aged 10-14 years. This condition threatens the quality of future human resources and impacts demographic bonus achievements and healthcare costs for NCD management. To address this, a self-monitoring application for NCDs (Monitoring Mandiri-Penyakit Tidak Menular or MM-PTM) has been developed to allow adolescents to independently surveil NCD risk factors. This study aims to evaluate user acceptance of the MM-PTM application. A total of 210 undergraduate students used this application and assessed its acceptance by completing a Technology Acceptance Model (TAM) questionnaire. The TAM questionnaire measures four latent constructs: Perceived Ease of Use, Perceived Usefulness, Attitude Toward Using Technology, and Behavioral Intention To Use. The questionnaire was validated and tested for reliability before use. Multiple linear regression analysis showed that Perceived Usefulness and Attitude Toward Using Technology positively correlated with Behavioral Intention To Use (all p-values < 0.001). This study revealed that Attitude Toward Using Technology is the dominant factor influencing Behavioral Intention To Use the MM-PTM application.