This editorial was written by early career scientists in soil science and gives an overview of the articles published in the special issue “Soil Science Challenges—An Interdisciplinary Overview of Current and Future Topics” on the occasion of the 100th anniversary of Journal of Plant Nutrition and Soil Science. A broad range of articles addressing soil carbon dynamics from the microscale to landscape scale, multi‐dimensional modeling, improved land management practices, nutrient cycles, soil hydrology, plastic in soils, and interdisciplinarity of soil science is covered in this issue.