The Neutrino oscillations have provided an excellent opportunity to study new-physics beyond the Standard Model, popularly known as BSM. The unknown couplings involving neutrinos, termed non-standard interactions (NSI), may appear as ‘new-physics’ in different neutrino experiments. The neutrino NSI offers significant effects on neutrino oscillations and CP-sensitivity, which may be probed in various neutrino experiments. The idea of neutrinos coupling with a scalar has evolved recently and looks promising. The effects of scalar NSI may appear as a perturbation to the neutrino mass matrix in the neutrino Hamiltonian. It modifies the neutrino mass matrix and may provide a direct possibility of probing neutrino mass models. As the scalar NSI affects the neutrino mass matrix in the Hamiltonian, its effect is energy independent. Moreover, the matter effects due to scalar NSI scales linearly with the matter density.In this work, we have performed a model-independent study of the effects of scalar NSI at long baseline neutrino experiments, taking DUNE as a case study. We have performed such a thorough study for DUNE for the first time. Various neutrino parameters may get affected due to the inclusion of scalar NSI as it modifies the effective mass matrix of neutrinos. We have explored the impact of scalar NSI in neutrino oscillations and its impact on the measurements of various mixing parameters. We have probed the effects of scalar NSI on different oscillation channels relevant to the experiment. We have also explored the impact of various possible elements in the scalar NSI term on the CP-violation sensitivity at DUNE.