A model for nematodiasis in New Zealand lambs: The effect of drenching regime and grazing management on the development of anthelmintic resistance

Leathwick, Dave M.; Vlassoff, A.; Barlow, N. D.

doi:10.1016/0020-7519(95)00059-3

Cited by 71 publications

(41 citation statements)

References 29 publications

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“…Simulations were run using the model previously described by Leathwick et al (1992Leathwick et al ( , 1995. Briefl y, the model describes the development and survival of free-living parasite stages on pasture in a suite of paddocks.…”

Section: Model Simulationsmentioning

confidence: 99%

Managing anthelmintic resistance: Untreated adult ewes as a source of unselected parasites, and their role in reducing parasite populations

Leathwick¹,

Miller²,

Atkinson³

et al. 2008

New Zealand Veterinary Journal

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Untreated adult ewes were a source of unselected genotypes, capable of slowing the development of anthelmintic resistance in most, but not all, parasite species. Further, the potential of adult ewes to remove from pasture more parasite larvae than they contribute through faecal contamination indicates a potentially useful role in suppressing parasite populations, particularly when worm control in lambs is less effective as a result of anthelmintic resistance.

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Section: Model Simulationsmentioning

confidence: 99%

Managing anthelmintic resistance: Untreated adult ewes as a source of unselected parasites, and their role in reducing parasite populations

Leathwick¹,

Miller²,

Atkinson³

et al. 2008

New Zealand Veterinary Journal

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“…Early recommendations for sustainable parasite control were either based on evidence regarding key molecular processes involved in selection for resistance (Dobson et al, 2001), or simulation models (Leathwick et al, 1995). In recent years, several observational studies (Suter et al, 2004;Lawrence et al, 2006;Hughes et al, 2007;Calvete et al, 2012) and clinical trials Leathwick et al, 2008;Waghorn et al, 2008Waghorn et al, , 2009 have been performed to investigate the association between putative risk factors and AHR.…”

Section: Introductionmentioning

confidence: 99%

A systematic review and meta-analysis of factors associated with anthelmintic resistance in sheep

Falzon

O’Neill

Menzies

et al. 2014

Preventive Veterinary Medicine

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“…In order to obtain a more sustainable control of these parasitic diseases, recent suggestions have been debated and proposed which take into consideration these differences by restricting treatments to the youngest animals of the flock in cattle [72] or sheep [46]. In goats, a lower divergence exists in the level of infection between young and adult goats which probably reflects the low ability of goats to develop an immune response against gastrointestinal nematodes [27,37].…”

Section: Identification Of Less Resistant Animals In Relation With Agementioning

confidence: 99%

Control of gastrointestinal parasitism with nematodes in dairy goats by treating the host category at risk

Hoste¹,

Chartier

Frileux

2002

Vet. Res.

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-Infections of the gastrointestinal tract with parasitic nematodes remain one of the main limiting factors in grazing dairy goats. The usual mode of control of these parasitic diseases has up to now been based on the repeated use of anthelmintics. However, the prevalence rates of anthelmintic resistances, in particular to benzimidazoles, are now particularly high in the French dairy goat production. This situation makes it mandatory to reconsider the usual mode of control of these nematodes and to look for short term, alternative solutions which combine the control of gastrointestinal infections and management of anthelmintic resistances. One of the possible options is to leave a part of the flock without treatment during the grazing season in order to maintain alleles of susceptibility to anthelmintics within the worm populations. Previous epidemiological observations identifying the categories of host populations at risk are presented which provide the rationale for targeted applications of treatments. The results of assays on experimental flocks and from farm surveys examining the advantages and drawbacks of selective treatments are presented. The value of these results in combination with other alternative solutions of control are discussed in order to use minimum treatments with maximum benefits. dairy goat / anthelmintic / selective treatment / anthelmintic resistance / parasitic nematode Résumé -Maîtrise des strongyloses gastro intestinales chez les chèvres laitières par l'application de traitements ciblés. Les infestations par les nématodes du tractus gastro intestinal demeurent un des principaux facteurs limitant à l'élevage des chèvres laitières au pâturage. Le mode usuel de maîtrise de ce parasitisme reposait jusqu'à présent sur un usage répété de molécules anthelminthiques. Cependant, la prévalence des lignées résistantes aux anthelminthiques, en particulier aux benzimidazoles, en éle-vage caprin laitier en France, est désormais très élevée. Ce constat oblige à rechercher rapidement des 531

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A model for nematodiasis in New Zealand lambs: The effect of drenching regime and grazing management on the development of anthelmintic resistance

Cited by 71 publications

References 29 publications

Managing anthelmintic resistance: Untreated adult ewes as a source of unselected parasites, and their role in reducing parasite populations

Managing anthelmintic resistance: Untreated adult ewes as a source of unselected parasites, and their role in reducing parasite populations

A systematic review and meta-analysis of factors associated with anthelmintic resistance in sheep

Control of gastrointestinal parasitism with nematodes in dairy goats by treating the host category at risk

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