A model of dual control mechanisms through anterior cingulate and prefrontal cortex interactions

Pisapia, Nicola De; Braver, Todd S.

doi:10.1016/j.neucom.2005.12.100

Cited by 206 publications

(279 citation statements)

References 5 publications

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“…One possibility is the dual mechanisms of control account (Braver, 2012;Braver, Gray, & Burgess, 2007;De Pisapia & Braver, 2006). According to this account, proactive control (i.e., preparatory attentional control) requires reliable contextual information in order to prepare for perceptual inputs, some information of which might be temporal in nature.…”

Section: List-level Proportion Congruent Effect 27mentioning

confidence: 99%

Time-out for conflict monitoring theory: Preventing rhythmic biases eliminates the list-level proportion congruent effect.

Schmidt¹

2017

Canadian Journal of Experimental Psychology / Revue canadienne

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The proportion congruent (PC) effect is the observation that congruency effects are smaller when most trials are incongruent rather than congruent. The list-level PC (LLPC) effect is the finding that a PC effect can transfer from biased inducer items to unbiased diagnostic items.Such effects are generally interpreted as resulting from conflict monitoring and attentional adaptation. An alternative view proposes that PC effects result from simple learning biases unrelated to conflict. The temporal learning account proposes that LLPC effects stem from a different task rhythm in the mostly congruent and mostly incongruent conditions. Two primeprobe experiments provide a critical test of this notion. In both, half of the participants were forced to withhold responding for a short period of time on inducer trials. This equates the task rhythm in the mostly congruent and mostly incongruent lists, while still maintaining differing levels of conflict. Consistent with the temporal learning account, but inconsistent with the conflict monitoring account, the LLPC effect was eliminated when rhythms were equated.

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Section: List-level Proportion Congruent Effect 27mentioning

confidence: 99%

Time-out for conflict monitoring theory: Preventing rhythmic biases eliminates the list-level proportion congruent effect.

Schmidt¹

2017

Canadian Journal of Experimental Psychology / Revue canadienne

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“…That result strongly suggests that the cognitive control strategy used to treat a same stimulus is dependant of the context, and therefore could be the object of inter-individual differences within a same population. Proactive and reactive control mechanisms are also supposed to be clearly dissociable in terms of cerebral networks involved (Braver, 2012;Braver et al, 2007;De Pisapia & Braver, 2006). Proactive control would be underlined by the ability to actively sustain inputs in lateral PFC while reactive control processes would be associated with transient activations within the lateral PFC, but also the anterior cingulate cortex (ACC).…”

Section: Introductionmentioning

confidence: 99%

Modulating effect of COMT Val158Met polymorphism on interference resolution during a working memory task

Jaspar

Dideberg

Maquet

et al. 2015

Brain and Cognition

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Jaspar M., Dideberg V., Bours V. Maquet P., Collette F. (2015). Modulating Effect of COMT Val 158 Met Polymorphism on Interference Resolution during a Working Memory Task. Brain and Cognition (In press)2 Abstract Genetic variability related to the catechol-O-methyltransferase (COMT) gene has received increasing attention in the last 15 years, in particular as a potential modulator of the neural substrates underlying inhibitory processes and updating in working memory (WM). In an event-related functional magnetic resonance imaging (fMRI) study, we administered a modified version of the Sternberg probe recency task (Sternberg, 1966) to 43 young healthy volunteers, varying the level of interference across successive items. The task was divided into two parts (high vs. low interference) to induce either proactive or reactive control processes. The participants were separated into three groups according to their COMT Val 158 Met genotype [Val/Val (VV); Val/Met (VM); Met/Met (MM)]. The general aim of the study was to determine whether COMT polymorphism has a modulating effect on the neural substrates of interference resolution during WM processing. Results indicate that interfering trials were associated with greater involvement of frontal cortices (bilateral medial frontal gyrus, left precentral and superior frontal gyri, right inferior frontal gyrus) in VV homozygous subjects (by comparison to Met allele carriers) only in the proactive condition of the task. In addition, analysis of peristimulus haemodynamic responses (PSTH) revealed that the genotype-related difference observed in the left SFG was specifically driven by a larger increase in activity from the storage to the recognition phase of the interfering trials in VV homozygous subjects. These results confirm the impact of COMT genotype on inhibitory processes during a WM task, with an advantage for Met allele carriers. Interestingly, this impact on frontal areas is present only when the level of interference is high, and especially during the transition from storage to recognition in the left superior frontal gyrus.Keywords: COMT gene -Working memory -fMRI -Cognitive control 3 IntroductionIn the last two decades, several lines of evidence have suggested that the neurotransmitter dopamine (DA) plays an important role in cognitive functions associated with prefrontal activity (Braver & Cohen, 1999;Cropley et al., 2006;Mattay et al., 2002). The study of the influence of DA on cognition in healthy populations appears particularly relevant given the long hypothesized role of DA in schizophrenia (Carlsson et al., 2000), a pathology that is well known to be associated with cognitive impairments (in particular in the executive domain). In that general context, genetic variability related to the catechol-Omethyltransferase (COMT) gene has received increasing attention as a potential modulator of executive functioning (Witte & Flöel, 2012). The human COMT gene codes for the major enzyme involved in the metabolic degradation of released DA. This gene, located on the lon...

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“…Importantly, both mechanisms of control are supposed to be clearly dissociable according to the underlying brain regions and the temporal pattern of this neural activity (Braver, 2012;Braver, et al, 2007;De Pisapia and Braver, 2006). Proactive control is supposed to be associated with sustained activation of lateral prefrontal cortex, which would reflect the active maintenance of tasks' goals and instructions.…”

Section: Introductionmentioning

confidence: 99%

Modulating effect of COMT genotype on the brain regions underlying proactive control process during inhibition

Jaspar

Genon

Muto

et al. 2014

Cortex

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Jaspar M., Genon S., Muto V., Meyer C., Manard M., Dideberg V., Bours V., Salmon E., Maquet P., Collette F. (2013). Modulating effect of COMT genotype on the brain regions underlying proactive control process during inhibition. Cortex (in press). DOI: http://dx.doi.org/10.1016DOI: http://dx.doi.org/10. /j.cortex.2013 Modulating effect of COMT genotype on the brain regions underlying proactive control process during inhibition

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A model of dual control mechanisms through anterior cingulate and prefrontal cortex interactions

Cited by 206 publications

References 5 publications

Time-out for conflict monitoring theory: Preventing rhythmic biases eliminates the list-level proportion congruent effect.

Time-out for conflict monitoring theory: Preventing rhythmic biases eliminates the list-level proportion congruent effect.

Modulating effect of COMT Val158Met polymorphism on interference resolution during a working memory task

Modulating effect of COMT genotype on the brain regions underlying proactive control process during inhibition

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