A model of furfural-inhibited growth and xylitol production by Candida magnoliae TISTR 5663

Wannawilai, Siwaporn; Chisti, Yusuf; Sirisansaneeyakul, Sarote

doi:10.1016/j.fbp.2017.07.002

Cited by 23 publications

(6 citation statements)

References 28 publications

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“…The pretreatment of lignocellulosic material generates several derivative compounds that disrupt the saccharification and fermentation processes [35][36][37][38]. To avoid inhibition of both processes, we used pure xylan as an assumption.…”

Section: Model Simulation Model Assumptions and Boundary Conditionsmentioning

confidence: 99%

“…Overall, the developed kinetic model simulation has been applied to design the configuration and the SSF operation process. However, the model could be further improved by incorporating non-ideal conditions such as the inhibitory term to the hydrolysis process [35] or the inhibitory term to the xylitol fermentation pro-cess [6,37,38], giving a more accurate estimation of the SSF process of lignocellulosic material. In addition, detailed kinetics of the related process and the estimated concentration of the inhibitory substance in a specific process, for example, SSF of OPEFB, needed to be defined.…”

Section: Comparison Of Configurations Of All Processesmentioning

confidence: 99%

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Modelling Based Analysis and Optimization of Simultaneous Saccharification and Fermentation for the Production of Lignocellulosic-Based Xylitol

Hidayatullah

Makertihartha

Setiadi

et al. 2021

Bull. Chem. React. Eng. Catal.

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Simultaneous saccharification and fermentation (SSF) configuration offers efficient use of the reactor. In this configuration, both hydrolysis and fermentation processes are conducted simultaneously in a single bioreactor, and the overall processes may be accelerated. However, problems may arise if both processes have different optimum conditions, and therefore process optimization is required. This paper presents a mathematical model over SSF strategy implementation for producing xylitol from the hemicellulose component of lignocellulosic materials. The model comprises the hydrolysis of hemicellulose and the fermentation of hydrolysate into xylitol. The model was simulated for various process temperatures, prior hydrolysis time, and inoculum concentration. Simulation of the developed kinetics model shows that the optimum SSF temperature is 36 °C, whereas conducting prior hydrolysis at its optimum hydrolysis temperature will further shorten the processing time and increase the xylitol productivity. On the other hand, increasing the inoculum size will shorten the processing time further. For an initial xylan concentration of 100 g/L, the best condition is obtained by performing 21-hour prior hydrolysis at 60 °C, followed by SSF at 36 °C by adding 2.0 g/L inoculum, giving 46.27 g/L xylitol within 77 hours of total processing time. Copyright © 2021 by Authors, Published by BCREC Group. This is an open access article under the CC BY-SA License (https://creativecommons.org/licenses/by-sa/4.0).

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Section: Model Simulation Model Assumptions and Boundary Conditionsmentioning

confidence: 99%

Section: Comparison Of Configurations Of All Processesmentioning

confidence: 99%

Modelling Based Analysis and Optimization of Simultaneous Saccharification and Fermentation for the Production of Lignocellulosic-Based Xylitol

Hidayatullah

Makertihartha

Setiadi

et al. 2021

Bull. Chem. React. Eng. Catal.

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show abstract

“…Overall, simulation of the developed kinetic model has been applied to design the configuration and the operational of SSF process. The model could be further improved by the incorporation of non-ideal conditions such as the inhibitory term to the hydrolysis process [43] or the inhibitory term to xylitol fermentation process [7,44,45] to give a more accurate estimation of the SSF process of lignocellulosic material. Details kinetics of the related process as well as the estimated concentration of inhibitory substance in a specific process, for example SSF of OPEFB, needed to be defined.…”

Section: Comparison Of Configurations Of All Processesmentioning

confidence: 99%

Modelling Based Analysis and Optimization of Simultaneous Saccharification and Fermentation for the Production of Lignocellulosic-Based Xylitol

Hidayatullah

Setiadi

Kresnowati

2021

Preprint

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Simultaneous saccharification and fermentation (SSF) configuration offers an efficient used of the reactor. In this configuration, both the hydrolysis and fermentation processes are conducted simultaneously in a single bioreactor and the overall process may be accelerated. Problems may arise if both processes have different optimum conditions, and therefore process optimization is required. This paper presents the development of mathematical model over SSF strategy implementation for producing xylitol from hemicellulose component of lignocellulosic materials. The model comprises of the hydrolysis of hemicellulose and the fermentation of hydrolysate into xylitol. The model was simulated for various process temperature, prior hydrolysis time, and inoculum concentration. Simulation of the developed kinetics model shows that the optimum SSF temperature is 36oC, whereas conducting a prior hydrolysis at its optimum hydrolysis temperature will further shorten the processing time and increase the xylitol productivity. On the other hand, increasing the inoculum size will shorten the processing time further. For an initial xylan concentration of 100 g/L, the best condition is obtained by performing 21-hour prior hydrolysis at 60oC, followed by SSF at 36oC by adding 2.0 g/L inoculum, giving 46.27 g/L xylitol within 77 hours of total processing time.

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“…Microorganisms that play a role in the formation of xylitol in the fermentation of hemicellulose biomass are various types of yeast. Some types of yeast used are Candida guilliermondii FTI 20037 and Debaromyces hansenii (NRRL Y-7426) [1], Candida tropicalis MTCC 184 [9], Candida guilliermondii FTI 20037 [3], Candida nepalensis [7], Candida magnolia TISTR 5663 [23], Komagatela pastoris [24], Saccharomyces cerevisiae PE-2 [10], Candida tropicalis MTCC 6192 [11], Candida tropicalis [20], [25], and Kluyveromyces marxianus ATCC 36907 [22]. According to Dhar et al [21], apart from xylose, xylitol could also be produced from arabinose where xylose and arabinose were transported through microorganism cells.…”

Section: Mechanism Of Formation Of Xylitol By Microorganismsmentioning

confidence: 99%

Chemical and Biotechnological Methods for the Production of Xylitol: A Review

Subroto¹

2020

IJETER

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Xylitol is a type of alcohol sugar that is often used in various pharmaceutical and food industries. Xylitol can be produced from raw materials that contain lots of hemicelluloses. Hemicellulose is commonly found in various agricultural wastes such as bagasse, corncobs, oil palm bunches, and others. This review discusses various methods for xylitol production. In general, the production of xylitol uses chemical and biotechnological processes. Chemical production is generally carried out by hydrolysis using chemical catalysts or metals, while the biotechnological production is carried out by enzymatic and fermentation utilizing the role of microorganisms. Xylitol production in biotechnological methods has been developing rapidly to replace chemical production because xylitol yields are high and are environmentally friendly.

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A model of furfural-inhibited growth and xylitol production by Candida magnoliae TISTR 5663

Cited by 23 publications

References 28 publications

Modelling Based Analysis and Optimization of Simultaneous Saccharification and Fermentation for the Production of Lignocellulosic-Based Xylitol

Modelling Based Analysis and Optimization of Simultaneous Saccharification and Fermentation for the Production of Lignocellulosic-Based Xylitol

Modelling Based Analysis and Optimization of Simultaneous Saccharification and Fermentation for the Production of Lignocellulosic-Based Xylitol

Chemical and Biotechnological Methods for the Production of Xylitol: A Review

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