Abstract. Previous studies suggest that online resilience, which is the capacity to bounce back from adversity by, for instance, coping with online risks in an effective way, and digital literacy serve as potential safeguards for young people against harmful consequences of negative online experiences. However, research on these factors largely resides in separate bodies of literature. By means of a systematic review, we aim to integrate the literature on young people’s online resilience, digital literacy, and well-being in the context of negative online experiences, and we examine the associations among them. The review of 30 empirical articles shows that negative online experiences undermine young people’s well-being but are also essential to developing online resilience. While a limited number of studies have focused on the protective roles of online resilience and digital literacy and on the link between these two factors, the review identified that more research is needed to establish whether this is truly the case. The review enables us to propose guidelines for further empirical research on the relations among young people’s digital literacy, online resilience, and well-being.