This paper is devoted to an inverse space-dependent source problem for spacefractional diffusion equation. Furthermore, we show that this problem is ill-posed in the sense of Hadamard, i.e., the solution (if it exists) does not depend continuously on the data. In addition, we propose a simplified generalized Tikhonov regularization method and prove the corresponding convergence estimates by using a priori regularization parameter choice rule and a posteriori parameter choice rule, respectively. Finally, numerical examples are carried to support the theoretical results and illustrate the effectiveness of the proposed method.