A molecular epidemiology survey of cutaneous leishmaniasis in patients referring to Parasitology Lab at Shiraz School of Medicine and the importance of PCR assay

Fakhar, Mehdi; Mikaeili, Fattaneh; Hatam, GR; Habibi, P; Karamian, Mehdi; Motazedian, MohammadHosain; Banimostafavi, Elham Sadat

doi:10.29252/jmj.8.1.2

Cited by 6 publications

(4 citation statements)

References 6 publications

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“…However, the distribution of CL by the age groups showed higher prevalence rate of disease in the age group 1-10 years. In agreement with the previous studies carried out in Shiraz, Gonbad, and Golestan provinces of Iran, which showed that the prevalence of infection is higher in children [18,19]. Higher prevalence rates among children might be due to the fact that children tend to be highly active at this age and spend most of their time outdoors; furthermore, their clothing makes them susceptible to mosquito bites [20].…”

Section: Discussionsupporting

confidence: 90%

Epidemiology, Associated Factors and Treatment Methods of Cutaneous Leishmaniasis Based on Previous Data from 2013 to 2018 in Ilam, Western Iran

et al. 2020

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Objective The aim of this study was to evaluate the epidemiology, clinical presentation and types of treatment of cutaneous leishmaniasis (CL) in the province of Ilam (Western Iran) in 5 years (from May 2013 to January 2018). This cross-sectional study involved patients diagnosed with CL who were referred to Mehran City Health center. Methods All patients were diagnosed by clinical and parasitological (Giemsa staining of lesion to observe the parasite) methods. Moreover, a structured questionnaire on demographic data including age, sex, occupation, number and site of the lesions, treatment regimen was administered to each case. Results In total, 2001 positive CL cases were observed in this study. The highest prevalence of CL was reported in the autumn season and mainly among male subjects residing in urban communities. The prevalence of CL varied with the age group: higher in the age group of 1-10 years than other groups. Besides, hands and faces were the most affected regions of the body. Most of the cases (47.35%) were managed by topical treatment (glucantime) and cryotherapy followed by systemic treatment (pentavalent antimony) 26.85%. Conclusions The prevalence of disease varied with age, increasing the prevalence rate in children due to their habitats, the highest prevalence in autumn due to climatic conditions. These findings help to better discuss the prevention and treatment of infections.

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Section: Discussionsupporting

confidence: 90%

Epidemiology, Associated Factors and Treatment Methods of Cutaneous Leishmaniasis Based on Previous Data from 2013 to 2018 in Ilam, Western Iran

et al. 2020

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“…However, it is more prevalent in the 0-5 year age group. This result is consistent with those of previous studies conducted in Shiraz, Gonbad, and Golestan Province (13,14). This finding might be due to the fact that children at this age spend most of their time outdoors; moreover, their clothing make them susceptible to mosquito bites (15).…”

Section: Discussionsupporting

confidence: 83%

Cutaneous leishmaniasis: an epidemiological survey in Iran during 2013-2015

Nikouee

Soltanian

Babaee

et al. 2017

JNMS

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Background and Purpose: Cutaneous leishmaniasis is an endemic disease in different parts of Iran. The aim of this study was to investigate the epidemiology of cutaneous leishmaniasis in Zarrin Dasht, Fars, Iran, during 2013-2015 Methods: This descriptive, cross-sectional study was performed on 266 patients selected through census sampling method. Data such as gender, age, occupation, disease season, location of scar on the patient's body, and place of residence were gathered using a checklist and analyzed through descriptive statistics and nonparametric methods. Results:In this study, the majority of the patients were female (58.3%) within the age group of 0-5 years (66.2%), living in rural areas (53%). The highest incidence rate was observed in autumn (49.2%). The majority of lesions (49%) were observed in face. Conclusion:The results of this study showed that cutaneous leishmaniasis is an endemic disease in Zarrin Dasht, and it annually infects numerous people. Although the disease process has been declining during 2013-2015 in this region, this disease is still a health hazard and needs to be managed.

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“…As far as the anatomical location of the lesions on the patients' body is concerned, most of the lesions were found on the hand (26.7%) which is in accordance with the studies carried out in Shiraz (24), Gonbad Kavous (25), Bafgh, of Yazd (18) and Mazandaran (17). Conversely, in another study performed in Gonbad Kavous (10), the highest percentage of lesions was observed on the feet.…”

Section: Introductionsupporting

confidence: 87%

Epidemiological Survey of Cutaneous Leishmaniasis in Mazandaran Province, Northern Iran

et al. 2019

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Background & Aims of the Study: Cutaneous leishmaniasis (CL) is considered one of the most important human vector-borne diseases in Iran. The current study aimed to determine some epidemiological aspects of cutaneous leishmaniasis in Mazandaran, Northern Iran. Materials and Methods: This descriptive study was conducted using the epidemiological data, including demographic and clinical features collected from 379 patients diagnosed with leishmaniasis in health centers affiliated to the Deputy for Health Center of Mazandaran University of Medical Sciences within 2009-2017. The disease was diagnosed based on clinical information and direct microscopic examination of the samples. Data were analyzed in SPSS software using nonparametric Kruskal-Wallis and Mann-Whitney U tests. Results: A total number of 379 individuals were diagnosed with CL during a 9-year period. Considering the population in Mazandaran, the incidence rate was reported as 1.27 per 100,000 population. It was also revealed that most of the cases of CL (n=279; 73.6%) were males and the majority of patients (n=137; 36.1%) were in the 20-29 age group. In addition, the majority of the ulcers were observed in hand (n=152; 26.7%) and foot (n=129; 22.6%), respectively. Moreover, just one ulcer was spotted in most of the patients (n=143; 37.7%). As the final note, the incidence was at the highest level during autumn in November (n=61; 16.1%). Conclusion: As evidenced by the obtained results, cutaneous leishmaniasis poses a daunting challenge to the public health in Mazandaran. This disease can be attributed to several factors, including agricultural activities, animal husbandry, and frequent national and international holidaymakers' visits to the province. With this background in mind, the results of the currents study could contribute greatly to the effective control of this disease.

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A molecular epidemiology survey of cutaneous leishmaniasis in patients referring to Parasitology Lab at Shiraz School of Medicine and the importance of PCR assay

Cited by 6 publications

References 6 publications

Epidemiology, Associated Factors and Treatment Methods of Cutaneous Leishmaniasis Based on Previous Data from 2013 to 2018 in Ilam, Western Iran

Epidemiology, Associated Factors and Treatment Methods of Cutaneous Leishmaniasis Based on Previous Data from 2013 to 2018 in Ilam, Western Iran

Cutaneous leishmaniasis: an epidemiological survey in Iran during 2013-2015

Epidemiological Survey of Cutaneous Leishmaniasis in Mazandaran Province, Northern Iran

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