2023
DOI: 10.1101/2023.10.19.562724
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A molecularly distinct cell type in the midbrain regulates intermale aggression behaviors in mice

Chunyang Li,
Cheng Miao,
Yao Ge
et al.

Abstract: The periaqueductal gray (PAG) has been suggested as a central hub for defensive responses to threatening stimuli and regulation of aggression. However, little is known on the circuitry and molecular mechanisms that govern this regulation. Here, we investigate the role of a molecularly distinct cell type, Taschykinin 2-expressing neurons (Tac2+), located in dorsomedial PAG (dmPAG), in modulating aggression in a mouse resident-intruder model. Using a rabies-assisted input mapping strategy, we found that dmPAGTac… Show more

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