A Monte Carlo simulation for the estimation of patient dose in rest and stress cardiac computed tomography with a 320-detector row CT scanner

Geleijns, Jacob; Joemai, Raoul M. S.; Cros, M.; Hernandez-Giron, Irene; Calzado, A.; Dewey, Marc

doi:10.1016/j.ejmp.2015.08.008

Cited by 6 publications

(3 citation statements)

References 17 publications

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“…8,16,17 It should be noted, however, that these effective doses are only gross estimates, especially for partial body exposures, and may suffer from inherent relative uncertainties of about +40% due to methodological limitations. 18,19 Current recommended models for assessing radiation risk Current cancer risk models for low-radiation exposure often use the linear no-threshold (LNT) model, which assumes that the risk of cancer increases linearly with the exposure, and that the The opinions expressed in this article are not necessarily those of the Editors of the European Heart Journal or of the European Society of Cardiology.…”

Section: Introductionmentioning

confidence: 99%

DNA damage-associated biomarkers in studying individual sensitivity to low-dose radiation from cardiovascular imaging

et al. 2016

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Section: Introductionmentioning

confidence: 99%

DNA damage-associated biomarkers in studying individual sensitivity to low-dose radiation from cardiovascular imaging

et al. 2016

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“…First, radiation dose was calculated using conversion factors, and differences in these conversion factors can lead to important differences in the results and to challenges in comparing different studies. We have provided CT radiation doses calculated with both the 0.014 and the 0.026 mSv/mGy • cm conversion factors, but other conversion factors could have been selected (28). The 0.026 mSv/mGy • cm conversion factor more accurately reflects CT radiation doses because it is based on the International Commission on Radiation Protection 103 weighting factors and a cardiac field of view (11).…”

Section: Discussionmentioning

confidence: 99%

Evaluating Radiation Exposure in Patients with Stable Chest Pain in the SCOT-HEART Trial

Chiong¹,

Ramkumar²,

Weir³

et al. 2023

Radiology

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A ccurate diagnosis is central to treatment strategies for patients with stable symptoms who are suspected of having coronary artery disease (1). However, radiation exposure remains an important concern in cardiovascular imaging because of its relation to lifetime cancer risk (2-5). Coronary CT angiography (CTA), SPECT, myocardial perfusion imaging, and invasive coronary angiography (ICA) all involve radiation, with radiation doses varying between centers. The impact of a diagnostic strategy based on coronary CTA on long-term cumulative radiation exposure is currently uncertain. Short-term cumulative radiation exposure in patients presenting with stable chest pain has previously been assessed in the Prospective Multicenter Imaging Study for Evaluation of Chest Pain (PROMISE) trial, which compared functional testing to coronary CTA (6). They found that the median cumulative radiation exposure per patient at 90 days was lower in the coronary CTA group compared with the functional testing group, using the 0.014 mSv/mGy • cm conversion factor for CT. Participants who underwent coronary CTA had a lower radiation dose than those who underwent nuclear stress Background: In the Scottish Computed Tomography of the Heart (SCOT-HEART) trial in individuals with stable chest pain, a treatment strategy based on coronary CT angiography (CTA) led to improved outcomes. Purpose: To assess 5-year cumulative radiation doses of participants undergoing investigation for suspected angina due to coronary artery disease with or without coronary CTA. Materials and Methods:This secondary analysis of the SCOT-HEART trial included data from six of 12 recruiting sites and two of three imaging sites. Participants were recruited between November 18, 2010, and September 24, 2014, with follow-up through January 31, 2018. Study participants had been randomized (at a one-to-one ratio) to standard care with CT (n = 1466) or standard care alone (n = 1428). Imaging was performed on a 64-detector (n = 223) or 320-detector row scanner (n = 1466). Radiation dose from CT (dose-length product), SPECT (injected activity), and invasive coronary angiography (ICA; kerma-area product) was assessed for 5 years after enrollment. Effective dose was calculated using conversion factors appropriate for the imaging modality and body region imaged (using 0.026 mSv/mGy • cm for cardiac CT).Results: Cumulative radiation dose was assessed in 2894 participants. Median effective dose was 3.0 mSv (IQR, 2.6-3.3 mSv) for coronary calcium scoring, 4.1 mSv (IQR, 2.6-6.1 mSv) for coronary CTA, 7.4 mSv (IQR, 6.2-8.5 mSv) for SPECT, and 4.1 mSv (IQR, 2.5-6.8 mSv) for ICA. After 5 years, total per-participant cumulative dose was higher in the CT group (median, 8.1 mSv; IQR, 5.5-12.4 mSv) compared with standard-care group (median, 0 mSv; IQR, 0-4.5 mSv; P < .001). In participants who underwent any imaging, cumulative radiation exposure was higher in the CT group (n = 1345; median, 8.6 mSv; IQR, 6.1-13.3 mSv) compared with standard-care group (n = 549; median, 6.4 mSv; IQR, 3.4-9.2 mS...

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“…Geleijns et al utilized the Philips Tomoscan LX CT with 120 kV and 333 mAs, for chest ex am i na tion with a Pb thick ness of 10 mm. The re search ers in serted TLD-100 into the Rando phan tom with out con sid er ing the re la tion ship be tween D lung and the body-weights of the examinee, yield ing a D lung of ap prox i mately 44 mSv [16,17].…”

Section: Com Par I Son Of D Lung With Other Stud Iesmentioning

confidence: 99%

Extra radiation dose of lungs in male examinees during cardiac computed tomography

et al. 2017

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ag ing, The Af fil i ated Hos pi tal (group) of Putian Uni ver sity, Fujian, China 3 De part ment of Radiologic On col ogy, Chung Shan Med i cal Uni ver sity Hos pi tal, Chung Shan Med i cal Uni ver sity, Tai wan, Re pub lic of China 4 School of Med i cine, Chung Shan Med i cal Uni ver sity, Tai wan, Re pub lic of China, 5 De part ment of Nu clear Med i cine, Landseed Hos pi tal, Ping-jen, Tao-Yuan City, Tai wan, Re pub lic of China 6 De part ment of Med i cal Im ag ing and Ra dio log i cal Sci ences, Chung Shan Med i cal Uni ver sity, Tai wan, Re pub lic of China Sci en tific pa per

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A Monte Carlo simulation for the estimation of patient dose in rest and stress cardiac computed tomography with a 320-detector row CT scanner

Cited by 6 publications

References 17 publications

DNA damage-associated biomarkers in studying individual sensitivity to low-dose radiation from cardiovascular imaging

DNA damage-associated biomarkers in studying individual sensitivity to low-dose radiation from cardiovascular imaging

Evaluating Radiation Exposure in Patients with Stable Chest Pain in the SCOT-HEART Trial

Extra radiation dose of lungs in male examinees during cardiac computed tomography

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