2024
DOI: 10.1182/blood.2023022192
|View full text |Cite
|
Sign up to set email alerts
|

A moonlighting job for α-globin in blood vessels

Prabhodh S. Abbineni,
Srishti Baid,
Mitchell J. Weiss

Abstract: Red blood cells (RBC) express high levels of hemoglobin A tetramer (HbA, 22) to facilitate oxygen (O2) transport. Hemoglobin and related proteins are also expressed at lower levels in other tissues across the animal kingdom. Physiological functions for most non-erythroid globins likely derive from their ability to catalyze reduction-oxidation (redox) reactions via electron transfer through heme-associated iron. An interesting example is illustrated by the recent discovery that -globin without -globin is ex… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

0
0
0

Year Published

2024
2024
2024
2024

Publication Types

Select...
2

Relationship

0
2

Authors

Journals

citations
Cited by 2 publications
references
References 112 publications
0
0
0
Order By: Relevance