A Multi-Center Disclusion Time Reduction (DTR) Randomized Controlled Occlusal Adjustment Study Using Occlusal Force and Timing Sensors Synchronized with Muscle Physiology Sensors

Abstract

Objective—To perform a Randomized Controlled Trial (RCT) Disclusion Time Reduction (DTR) study at five Dental Colleges, using intraoral sensors and muscular electrodes. Methods and Materials—One hundred students were randomly assigned to a treatment group to receive the ICAGD coronoplasty, or a control group that received tooth polishing. All subjects answered symptom questionnaires: Beck Depression Inventory-II, Functional Restrictions, and Chronic Pain Symptom and Frequency. Subjects self-reported after ICAGD or placebo at 1 week, 1 month, 3 months, and 6 months. The Student’s t-Test analyzed the measured data. The Mann–Whitney U Test analyzed the subjective data (Alpha = 0.05). Results—The Disclusion Times, BDI-II scores, and Symptom Scales were similar between groups prior to treatment (p > 0.05). At 1 week, all three measures reduced in the treatment group, continuing to decline over 6 months (p < 0.05), but not for the controls (p > 0.05). Symptom Frequency, Functional Restrictions, and Pain Frequencies were higher in the treated group (p < 0.05), but declined after ICAGD compared to the control group (p < 0.05). Conclusions—ICAGD reduced Pain, Functional Restrictions, Symptom Frequency, and Emotional Depression within 1 week, which continued for 6 months. The tooth polishing did not initiate a placebo response.

Effect of Subgingival Scaling and Root Planing-assisted Occlusal Adjustment Scheme on Periodontitis

“…Furthermore, with the data obtained by the system, targeted adjustment can be achieved, so that occlusal contact re- mains consistent under light and heavy occlusal forces, thereby ensuring occlusal stability. TGF-β, a multifunctional cytokine, is capable of regulating the expression of several genes through signal transduction and associated reaction, which is involved in inflammatory responses, apoptosis, extracellular matrix metabolism, and other biological processes 20) . As a multi-effect cytokine secreted by various cells, IL-6 will have a rapid elevation in the case of attacking of the body by bacteria and viruses.…”

Effects of a video-viewing intervention with positive word stimulation on the depressive symptoms of older patients with cardiac disease and subthreshold depression: a pilot randomized controlled trial protocol

“…The intervention duration in this study was 1 week because the number of days of hospitalization should be considered in the acute care of patients with cardiac disease in Japan and the feasibility of data collection and the duration of possible rehabilitation intervention. The BDI-II is a self-report measure of depressive symptoms that assesses symptoms over the past 2 weeks; however, previous studies indicate that a 1-week intervention period can produce significant differences in the BDI-II [ 87 – 89 , 101 , 102 ]. For these reasons, we employed BDI-II in this study.…”