A multi-institutional international study of risk factors for hematoma after thyroidectomy

Campbell, Michael J.; McCoy, Kelly L.; Shen, Wen T.; Carty, Sally E.; Lubitz, Carrie C.; Moalem, Jacob; Nehs, Matthew A.; Holm, Tammy M.; Greenblatt, David Yü; Press, Danielle; Feng, Xiaoxi; Siperstein, Allan; Mitmaker, Elliot J.; Benay, Cassandre; Tabah, Roger; Oltmann, Sarah C.; Chen, Herbert; Sippel, Rebecca S.; Brekke, Andrew V.; Vriens, Menno R.; Lodewijk, Lutske; Stephen, Antonia E.; Nagar, Sapna; Angelos, Peter; Ghanem, Maher; Prescott, Jason D.; Zeiger, Martha A.; Han, Peijin; Sturgeon, Cord; Elaraj, Dina M.; Nixon, Iain J.; Patel, Snehal G.; Bayles, Stephen W.; Heneghan, Rachel E.; Ochieng, Peter; Guerrero, Marlon A.; Ruan, Daniel T.

doi:10.1016/j.surg.2013.06.032

Cited by 92 publications

(101 citation statements)

References 20 publications

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“…The age group distribution corresponds to the highest frequency of these diseases and is similar to studies with large numbers of participants (5,7,8). The prevalence of females is 7-fold higher than males, which contrasts The following surgical complications were associated with the procedure: hemorrhage in 41 cases (1.2%), permanent hypoparathyroidism in 10 cases (0.3%) and recurrent laryngeal nerve injury in 23 cases (0.7%) ( Table 4).…”

Section: Discussionsupporting

confidence: 84%

“…Taking into account studies associating the experience of surgeons or reference centers in these procedures (4,5), the results obtained in our service, which performs more than 200 thyroid surgeries per year, would be in agreement with a study from Maryland that included 5,860 patients and surgeons who performed more than 100 thyroid surgeries per year with lower complication rates (15,19).…”

Section: Thyroid Surgery Performed On An Overnight Basissupporting

confidence: 87%

“…In 1883, he published a study including 43 thyroidectomies with a mortality rate of 6.9% that contrasted with the rates above 20% observed at the time. The contribution of Kocher to the development of thyroid surgery was so important that, in 1909, he was awarded the Nobel Prize in medicine (4,5). Notably, in 1927, with the technique standardized and 5,000…”

Section: Introductionmentioning

confidence: 99%

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Thyroid surgery performed on an overnight basis: a 17 years of experience

Molinari

Treiguer

Gava

et al. 2015

Arch. Endocrinol. Metab.

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Objective: This study aimed to evaluate the results of thyroid surgeries with hospitalization periods shorter than 18 hours performed in a surgical endocrinology service, correlating these results with type of procedure, the definitive diagnosis and complications associated with the procedure. Subjects and methods: The procedures performed, complications associated, hospitalization period, and relationships among these variables were assessed in consecutive patients subjected to different types of thyroid surgeries from January 1997 to March 2014 by the same group of surgeons. Data were analyzed by frequency, and the associations between the hospitalization period and other variables were analyzed using the Pearson chi-square test and Fisher's exact test, using a multiple comparisons test with Bonferroni correction. Results: Among the 3,411 surgeries performed, 799 of them were malignant neoplasia, 2,505 were benign tumors and 107 were Graves' disease. The following procedures were performed: total thyroidectomy (1597 patients); total thyroidectomy with neck exploration (369 patients); lobectomy plus isthmectomy (1084 patients); total thyroidectomy complementation (145 patients); total thyroidectomy with neck dissection (84 patients); modified radical total thyroidectomy (13 patients); nodulectomy (11 patients); unresectable (9 patients); central neck dissection (48 patients); lateral neck dissection (38 patients); and others (13 patients). The following surgical complications, characteristic of the procedure: hemorrhage in 41 (1.2%) patients, hypoparathyroidism in 10 (0.3%) patients and recurrent laryngeal nerve (RLN) injury in 23 (0.7%) patients. Hospitalization shorter than 18 hours was observed in 97% of patients. Conclusion: Thyroid surgery can be safely performed in virtually all patients on an overnight basis in specialized services. Arch Endocrinol Metab.2015;59(5):

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Section: Discussionsupporting

confidence: 84%

Section: Thyroid Surgery Performed On An Overnight Basissupporting

confidence: 87%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Thyroid surgery performed on an overnight basis: a 17 years of experience

Molinari

Treiguer

Gava

et al. 2015

Arch. Endocrinol. Metab.

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“…Although thyroidectomy is curative for Graves' disease and morbidity is low at high volume centers (32), Hallgrimsson et al and Welch et al both found Graves' disease to be associated with increased morbidity, specifically hypocalcemia, following total thyroidectomy (33,34). Campbell et al investigated risk factors for hematoma after thyroidectomy and found Graves' disease to be independently associated with hematoma post-thyroidectomy (35). Within this group of hyperthyroid patients, those treated with Lugol's potassium iodide drops, had ophthalmopathy, or had the presence of antithyroglobulin antibodies preoperatively, were noted to have more difficult operations based on the TDS system.…”

Section: Discussionmentioning

confidence: 99%

Identifying Predictors of a Difficult Thyroidectomy

Mok

Oltmann

Chen

et al. 2014

Journal of Surgical Research

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“…Nevertheless, postoperative haemorrhage remains an uncommon but potentially life-threatening complication of thyroid surgery. The risk for a postoperative hemorrhage to happen ranges from 0.5% and 6.5% [5] [7] [9] [10].…”

Section: Introductionmentioning

confidence: 99%

Comparison of an Intraoperative Application of a Haemostatic Agent (PerClot<sup>&reg</sup>) with Conventional Haemostatic Procedure after Thyroid Resection

Ahnen¹,

Ahnen²,

Wirth³

et al. 2015

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Background: Postoperative hemorrhage remains an uncommon but potentially life-threatening complication of thyroid surgery. The aim of this case-controlled study was to compare the effectiveness of PerClot ® hemostatic agent with hemostasis by conventional technique (HCT) in thyroid surgery. Methods: The thyroid resection was performed from November 2009 to February 2010. Exclusion criteria were applied. There were 30 patients in the HCT group and 30 patients in the PerClot ® group. The outcome parameters were postoperative bleeding, the drainage volume 24 hours postoperatively and adverse events according to PerClot ® . Results: There was no postoperative hemorrhage in both groups. We found no significant difference between the control and PerClot ® group with regard to total drainage volume after 24 h (51 ml ± 36.9 control group/53 ml ± 39.5 PerClot ® group (p = 0.79)). There were no adverse events in the PerClot ® group. Conclusions: Routine use of PerClot ® hemostatic agent has no advantage over conventional hemostasis technique (HCT) in thyroid surgery. In addition, PerClot ® is safe and well tolerated.

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A multi-institutional international study of risk factors for hematoma after thyroidectomy

Cited by 92 publications

References 20 publications

Thyroid surgery performed on an overnight basis: a 17 years of experience

Thyroid surgery performed on an overnight basis: a 17 years of experience

Identifying Predictors of a Difficult Thyroidectomy

Comparison of an Intraoperative Application of a Haemostatic Agent (PerClot<sup>&reg</sup>) with Conventional Haemostatic Procedure after Thyroid Resection

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A multi-institutional international study of risk factors for hematoma after thyroidectomy

Cited by 92 publications

References 20 publications

Thyroid surgery performed on an overnight basis: a 17 years of experience

Thyroid surgery performed on an overnight basis: a 17 years of experience

Identifying Predictors of a Difficult Thyroidectomy

Comparison of an Intraoperative Application of a Haemostatic Agent (PerClot&lt;sup&gt;&amp;reg&lt;/sup&gt;) with Conventional Haemostatic Procedure after Thyroid Resection

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Comparison of an Intraoperative Application of a Haemostatic Agent (PerClot<sup>&reg</sup>) with Conventional Haemostatic Procedure after Thyroid Resection