In ancient villages, the spread of uninterrupted fires caused great damage to clustered wooden houses. Thus, the spread of fire among wooden houses should be systematically studied to explore its characteristics. Statistical analysis is a feasible way to study the characteristics and underlying mechanisms of fire in full-scale wooden houses. In this study, 4 full-scale wooden buildings were built in an ethnic village in Guizhou Province, and the fire spread test was conducted by igniting a 0.63-MW power wood crib. To investigate the fire spread, the visual characteristics were observed, and the temperatures and heat radiation at special locations were monitored with thermocouples and radiation flowmeters, respectively. The effect of relative slope, heat radiation, and wind direction on fire spread characteristics was established by mathematical statistics, and the measured temperatures were used to verify the statistics’ regularity. The results showed that in wooden houses, fire spread was mainly influenced by the slope, the distance between houses, and wind direction. When the inner wall of a wooden house is protected by a fireproof coating, the thermal radiation spread and fire spread are both slower. The slope and distance had the same influence weight (0.41) on fire spread; however, since they affect the process in different ways, they should be analyzed separately for fire risk evaluation. The findings of this study provide a theoretical foundation for understanding the fire spread process in wooden buildings.