The evolution of the bone-implant interface reflects the implant osseointegration and bond strength, thereby determining the overall implant stability in the jawbone. Quantitative ultrasound represents a promising alternative technique to characterize the interfacial integrity, precisely due to the fact that those waves propagate essentially along the bone-implant interface, and are therefore influenced by its state. This study reports a numerical investigation of ultrasonic wave propagation for a commercial implant-jawbone system in which the thickness and mechanical properties of the interfacial layer (corresponding to the interphase) are systematically varied through the application of a rule of mixtures, in order to mimic the evolution from a dominantly soft tissue-like medium up to a fully healed bone. A simple figure of merit is devised in terms of an RMS-like (root mean square) factor based on the implant displacements, that evolves continuously and significantly with the bone "healing" process, thereby providing unequivocal information on the nature of the investigated bone-implant interface. The results show that the wave propagation pattern is primarily dictated by the impedance mismatch rather than by the interface thickness. This study validates the concept of quantitative ultrasonic testing as a sensitive alternative to the widespread resonant frequency analysis, thereby opening the way for future sensitivity analyses that will address more refined bone-implant interface pathologies such as those observed in the clinical realm.