A multicenter cohort study to compare quality of life in breast cancer patients according to sentinel lymph node biopsy or axillary lymph node dissection

Dabakuyo, Tienhan Sandrine; Fraisse, J.; Causeret, S.; Gouy, Sébastien; Padéano, Marie-Martine; Loustalot, Catherine; Cuisenier, Jean; Sauzedde, J.-M.; Smail, Marc; Combier, Jean-Philibert; Chevillote, Patrick; Rosburger, C; Boulet, Stéphanie; Arveux, Patrick; Bonnetain, Franck

doi:10.1093/annonc/mdp016

Cited by 38 publications

(31 citation statements)

References 26 publications

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“…Regular practice of either standard care alone or in combination with yoga improved arm and shoulder function and QoL significantly at 10 weeks post-surgery, and this effect was maintained at 6 months for both study groups. As reported in previous studies [34][35][36][37], improvement was greater in women who did not have axillary clearance or chemotherapy. In addition, older women (>65yrs) were less likely to complain about stiffness and pain in the operated arm and also reported higher QoL than younger women (<50yrs).…”

Section: Discussionsupporting

confidence: 82%

Post-operative exercises after breast cancer surgery: Results of a RCT evaluating standard care versus standard care plus additional yoga exercise

Harder

Langridge

Solis-Trapala

et al. 2015

European Journal of Integrative Medicine

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Section: Discussionsupporting

confidence: 82%

Post-operative exercises after breast cancer surgery: Results of a RCT evaluating standard care versus standard care plus additional yoga exercise

Harder

Langridge

Solis-Trapala

et al. 2015

European Journal of Integrative Medicine

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“…In every instance, the beneficial effect of SLNB on BC patient QoL, compared with ALND, was observed [9].…”

Section: Discussionmentioning

confidence: 95%

“…The design of this study has been described elsewhere [9]. Briefly, it was a multicenter prospective cohort study including all women operated on for BC as the primary treatment in five hospitals of the Côte d'Or and Saône-et-Loire.…”

Section: Patientsmentioning

confidence: 99%

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Time to Deterioration in Quality of Life Score as a Modality of Longitudinal Analysis in Patients with Breast Cancer

et al. 2011

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Purpose. This prospective multicenter study explored different definitions of time to deterioration (TTD) in quality of life (QoL) scores, according to different cutoffs of the minimal clinically important difference (MCID) as a modality for longitudinal QoL assessment in breast cancer patients.Methods. QoL was assessed using the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire C30 and BR-23 before surgery, after surgery, and 6 and 12 months later. The global health score, arm symptoms score (BRAS), and breast symptoms score were analyzed. For a given baseline score, QoL was considered to have deteriorated if this score decreased by >5 points at any time point after baseline. Analyses were repeated using an MCID of 10 points and taking the score after surgery as the reference score (to explore the occurrence of response shift). TTD was calculated using the Kaplan-Meier method and Cox regression was used to identify independent factors associated with TTD.Results. Two hundred thirty-five patients underwent axillary lymph node dissection (ALND), 222 underwent sentinel lymph node biopsy (SLNB), and 61 underwent SLNB plus ALND. Patients who underwent SLNB had a significantly longer TTD for the BRAS dimension than those who underwent ALND. Cox multivariate analyses showed that treatment using SLNB and age >59 years were independently associated with longer TTD for the

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“…However, in the acute survival phase [7,8], when oncological therapies are performed during the first year following diagnosis, the effect of therapies such as chemotherapy, radiotherapy, hormone therapy, and immunotherapy can overcome the lower aggressiveness of the surgery, leading to no differences in quality of life (QoL) between the two groups of patients [9][10][11][12].…”

Section: Introductionmentioning

confidence: 99%

Effectiveness of Physiotherapy Intervention on the Quality of Life of Women with Breast Cancer who Underwent Sentinel Lymph Node Biopsy.

Duarte¹,

Aguiar

Faria

et al. 2017

OSJ

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Purpose: To evaluate if physiotherapy can contribute to the quality of service provided to Women with Breast Cancer who underwent sentinel lymph node biopsy (SLNB).Methods: This Quasi-experimental study addressed a sample of 172 women with breast cancer who underwent surgery with SLNB, 90 were included in the control group and 82 in the experimental group. We used the EORTC C30 and BR23 questionnaires to collect data about the quality of life (QoL) in the course of the first 9 months after surgery. The experimental group was submitted to specific physiotherapy techniques while the control group was the target of assessments only. Poisson regression was used to perform the calculation of the Relative Benefit (aRB) and Relative Risk (aRR) adjusted for several confounding factors at the baseline of the study.Results: In the third month after surgery the experimental group showed a higher proportion of patients with substantial clinical improvement in the Global Health Status (GHS) (aRB=2.230; p=0.014) and a lower risk of degradation of the GHS (aRR=0.384; p=0.011), Physical Function (PF) (aRR=0.484; p=0.035), and Arm Symptoms (BRAS) (aRR=0.159; p=0.007), when compared to the control group. Between the 1st and 6th month after surgery, physiotherapy seems to act as a protective factor on the degradation of GHS and PF. Between the 1st and 9th month after surgery the experimental group showed a higher proportion of patients with notable clinical improvement in the GHS (aRB=1.905; p=0.038) and in the BRAS (aRB=1.761; p=0.029) and a lower risk of degradation of the GHS (aRR=0.287; p=0.010) and BRAS (aRR=0.265; p=0.0421) scales.Conclusions: In the course of the acute survival phase, physiotherapy can help to improve the QoL of women with breast cancer who underwent surgeries with SLNB, giving a positive contribution to the quality of service provided to this group of patients.

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A multicenter cohort study to compare quality of life in breast cancer patients according to sentinel lymph node biopsy or axillary lymph node dissection

Abstract: SLNB improved GHS and BRAS QoL in breast cancer patients. However, surgeons must be cautious, SLNB with ALND results in a poorer QoL.

Cited by 38 publications

References 26 publications

Post-operative exercises after breast cancer surgery: Results of a RCT evaluating standard care versus standard care plus additional yoga exercise

Post-operative exercises after breast cancer surgery: Results of a RCT evaluating standard care versus standard care plus additional yoga exercise

Time to Deterioration in Quality of Life Score as a Modality of Longitudinal Analysis in Patients with Breast Cancer

Effectiveness of Physiotherapy Intervention on the Quality of Life of Women with Breast Cancer who Underwent Sentinel Lymph Node Biopsy.

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