A multicenter study on the utility and safety of EBUS‐TBNA and EUS‐B‐FNA in children

Dhooria, DM Sahajal; Madan, Karan; Pattabhiraman, Vallandramam; Sehgal, DM Inderpaul Singh; Mehta, Ravindra; Vishwanath, D.; Srinivasan, DM Arjun; Sivaramakrishnan, Mahadevan; Mohan, Anant; Mathew, Joseph L; Kabra, Sushil Kumar; Md, DM Randeep Guleria; Behera, Digambar; Agarwal, Ritesh

doi:10.1002/ppul.23415

Cited by 57 publications

(71 citation statements)

References 42 publications

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“…The addition of EUS‐B‐FNA only in cases where the mediastinal lymph nodes were not accessible to EBUS‐TBNA, significantly increased the sensitivity of the procedure, which reached 100% in one study . The combined use of EBUS‐EUS‐B has been found safe and effective as part of the diagnostic evaluation in children with mediastinal lymphadenopathy …”

Section: Resultsmentioning

confidence: 99%

EBUS: Faster, cheaper and most effective in lung cancer staging

et al. 2018

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The use of endobronchial ultrasound trans-bronchial needle aspiration (EBUS-TBNA) as the initial diagnostic and staging procedure in patients with suspected, non-metastatic lung cancer has gained substantial support, and is now recommended by numerous guidelines. Whereas considerable attention has been pointed to the reductions in costs achieved by EBUS-TBNA, that has not been the case for some of its more significant benefits, namely the reduction of the diagnostic work-up time and its ability to accurately assess and restage lymph nodes, which were previously stated incorrectly by CT or PET scan. Both these benefits translate into improved outcomes for patients, as delays are reduced, futile surgeries are prevented and curable operations can be performed on patients previously excluded by CT or PET scan. Indeed, the use of EBUS as the initial diagnostic and staging procedure has been proven to significantly increase survival, compared with conventional diagnostic and staging procedures, in a pragmatic, randomised controlled trial (Navani N. et al, 2015). The instalment of EBUS will have the greatest effect on overwhelmed, suboptimally functioning national healthcare systems, by decreasing the number of required diagnostic and staging procedures, therefore reducing both treatment delays and costs. The improved selection of surgical candidates by EBUS will result in improved patient outcomes. The latest findings regarding the benefits of EBUS are outlined in this review, which, to the best of our knowledge, is the first to emphasise the impact of the procedure, both on timing and costs of lung cancer staging, as well as on survival.

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Section: Resultsmentioning

confidence: 99%

EBUS: Faster, cheaper and most effective in lung cancer staging

et al. 2018

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“…This indication is rarer in children, though mediastinal masses are sometimes seen. Dhooria et al reported results from a retrospective multicenter study on the use of this method in 67 children (3‐17 years old) for the diagnostic evaluation of mediastinal lymphadenopathy. Eighty percent of these patients were biopsied using only sedation and spontaneous breathing.…”

Section: Diagnostic Testing/endoscopymentioning

confidence: 99%

Pediatric Pulmonologyyear in review 2016: Part 1

et al. 2017

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Our journal covers a broad range of research and scholarly topics related to children's respiratory disorders. For updated perspectives on the rapidly expanding knowledge in our field, we will summarize the past year's publications in our major topic areas, as well as selected publications in these areas from the core clinical journal literature outside our own pages. The current review covers articles on neonatal lung disease, pulmonary physiology, and respiratory infection.Word count: 71 3

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“…To make a diagnosis, a tissue sample is needed, and traditionally this would be obtained via either open surgery or video-assisted thoracoscopic surgery. These procedures are invasive with a prolonged recovery time and potentially serious side effects 1. In adult medicine, less invasive methods of obtaining a biopsy have become routine, and these techniques are beginning to be used in the paediatric population (see table 1).…”

Section: Shivanthan Shanthikumar (Respiratory Fellow) and Jo Harrisonmentioning

confidence: 99%

“…No significant adverse events were reported. Dhooria et al 1 reviewed 67 paediatric patients who had either an EBUS TBNA performed, or the same equipment was placed in the oesophagus to obtain a transoesophageal biopsy (EUS-B-FNA). There was no difference in diagnostic yield between EBUS TBNA and EUS-B-FNA with a calculated diagnostic sensitivity of 79.1% for EBUS TBNA or EUS-B-FNA.…”

Section: Shivanthan Shanthikumar (Respiratory Fellow) and Jo Harrisonmentioning

confidence: 99%