A Multicentre Year-long Randomised Controlled Trial of Exercise Training Targeting Physical Functioning in Men with Prostate Cancer Previously Treated with Androgen Suppression and Radiation from TROG 03.04 RADAR

Galvão, Daniel A.; Spry, Nigel; Denham, James W.; Taaffe, Dennis R.; Cormie, Prue; Joseph, David; Lamb, David; Chambers, Suzanne K.; Newton, Robert U.

doi:10.1016/j.eururo.2013.09.041

Cited by 186 publications

(289 citation statements)

References 26 publications

Supporting

Mentioning

265

Contrasting

Unclassified

Order By: Relevance

“…Of the sixteen studies involving patients in active treatment [29][30][31][32][33][34][35][36][37][38][39][40][41][42][43][44] , six demonstrated that, compared with the control group, the intervention group experienced significant improvements in qol 30,31,33,[38][39][40]43 . In the thirteen post-treatment intervention studies 10,12,14,[45][46][47][48][49][50][51][52][53][54] , two reported similar significant differences between groups 46,49 .…”

Section: Quality Of Lifementioning

confidence: 97%

“…Of the sixteen rcts that measured muscular or aerobic fitness, or both 10,14,29,30,34,35,37,39,40,[44][45][46][47][48]52,54 , eleven found significant positive changes in the exercise groups 10,14,29,30,34,35,37,39,[44][45][46]48 . A systematic review found substantial increases in muscular strength and endurance with resistance training for patients on androgen deprivation therapy 21 .…”

Section: Muscular and Aerobic Fitnessmentioning

confidence: 99%

See 1 more Smart Citation

Exercise for People with Cancer: A Clinical Practice Guideline

et al. 2017

View full text Add to dashboard Cite

Background Development of this guideline was undertaken by the Exercise for People with Cancer Guideline Development Group, a group organized by Cancer Care Ontario’s Program in Evidence-Based Care (pebc). The purpose of the guideline was to provide guidance for clinicians with respect to exercise for patients living with cancer, focusing on the benefits of specific types of exercise, recommendations about screening requirements for new referrals, and safety concerns.Methods Consistent with the pebc’s standardized approach, a systematic search was conducted for existing guidelines, and systematic literature searches were performed in medline and embase for both systematic reviews and primary literature. Content and methodology experts performed an internal review, which was followed by an external review by targeted experts and intended users.Results The search identified three guidelines, eighteen systematic reviews, and twenty-nine randomized controlled trials with relevance to the topic. The present guideline provides recommendations for the duration, frequency, and intensity of exercise appropriate for people living with cancer. It also provides recommendations for pre-exercise assessment, safety concerns, and delivery models.Conclusions There is sufficient evidence to show that exercise provides benefits in quality of life and muscular and aerobic fitness for people with cancer both during and after treatment, and that it does not cause harm. The present guideline is intended to support the Canadian Society for Exercise Physiology’s Canadian physical activity guidelines. The recommendations are intended for clinicians and institutions treating cancer patients in Ontario, and for policymakers and program planners involved in the delivery of exercise programs for cancer patients.

show abstract

Section: Quality Of Lifementioning

confidence: 97%

Section: Muscular and Aerobic Fitnessmentioning

confidence: 99%

Exercise for People with Cancer: A Clinical Practice Guideline

et al. 2017

View full text Add to dashboard Cite

show abstract

“…[56,57] Patients and partners often have different perceptions about prostate cancer-related issues and difficulty discussing them. [58,59] Couples lack access to survivorship care programs because of suboptimal services and referrals, [60] and the small number of programs available [28] (especially those that are couple-focused [61][62][63][64][65][66][67]). In this study, integration of a couple-focused, tailored mHealth intervention into standard SCPs is an innovative approach to deliver survivorship care information to both cancer patients and their family caregivers, and to provide family and patient centered care.…”

Section: Principal Resultsmentioning

confidence: 99%

Enhancing Survivorship Care Planning for Patients With Localized Prostate Cancer Using a Couple-Focused mHealth Symptom Self-Management Program: Protocol for a Feasibility Study (Preprint)

Song¹,

Dunlap²,

Tan³

et al. 2017

Preprint

View full text Add to dashboard Cite

This project explores a new model of care that enhances survivorship care planning and promotes health for men with localized prostate cancer transitioning to post-treatment selfmanagement. Survivorship care planning is important for patients with prostate cancer because of its high incidence rate in the U.S., the frequent occurrence of treatment-related side effects, and reduced quality of life for both men and their partners. A key component of comprehensive survivorship care planning is survivorship care plans (SCPs), documents that summarize cancer diagnosis, treatment, and plans for follow-up care. However, research concerning the effectiveness of survivorship care plans (SCPs) on patient outcomes or health service use has thus far been inconclusive. SCPs that are tailored to individual patients' needs for information and care may improve effectiveness. In this study, we will examine the feasibility of an Enhanced Survivorship Care Plan (ESCP) that integrates a symptom self-management mHealth program called Prostate Cancer Education and Resources for Couples (PERC) into the existing standardized SCP. We will use a two-group randomized controlled pretest-posttest design and collect data at baseline (T1) and 4 months later (T2) among 50 patients completing initial treatment for localized prostate cancer and their partners. The specific aims are: Aim 1: Examine the feasibility of delivering ESCPs (as assessed by recruitment, enrollment, and retention rates, program satisfaction with the ESCP, and perceived ease of use of the ESCP). We will use mixed methods to achieve this aim. Aim 2: Estimate the magnitude of benefit of ESCPs. We hypothesize that, compared with the standardized SCP users, the ESCP users will report: (1) greater improvement in their primary outcomes of quality of life (overall, physical, emotional, and social quality of life); (2) greater improvement in secondary outcomes (reduction in negative appraisals and improvement in self-efficacy, social support, and health behaviors to manage symptoms); and (3) fewer visits to post-treatment care services from T1 (baseline) to T2 (four-month followup). The results from this study will help design a definitive randomized trial to test the efficacy of the ESCPs.

show abstract

“…Of the sixteen rcts that measured muscular or aerobic fitness or both 22,23,27,28,30,32,33,37,38,40,41,[43][44][45][46][47] , twelve found significant positive changes in the exercise groups (Table vi) 22,23,27,28,30,32,37,38,41,43,44,46 . One systematic review 14 found substantial increases in muscular strength and endurance with resistance training for patients on androgen deprivation therapy (Table v).…”

Section: Qol and Muscular And Aerobic Fitnessmentioning

confidence: 99%

“…Of the sixteen rcts involving patients in active treatment [22][23][24][25][26][27][28][29][30][31][32][33][34][35][36][37] , seven reported significant differences between the intervention and control groups (Table vi) 23,24,26,[31][32][33]36 . In the thirteen posttreatment intervention studies [38][39][40][41][42][43][44][45][46][47][48][49][50][51][52][53] , two reported significant qol improvement in the exercise groups 41,42 . In particular, patients with lymphedema experienced qol benefits, and aerobic and resistance exercises were both safe for women who had undergone breast and axillary surgery 6,7,38,39,44 .…”

Section: Qol and Muscular And Aerobic Fitnessmentioning

confidence: 99%

Exercise for people with cancer: a systematic review

et al. 2017

View full text Add to dashboard Cite

Background This systematic review was completed by the Exercise for People with Cancer Guideline Development Group, a group organized by Cancer Care Ontario’s Program in Evidence-Based Care (pebc). It provides background and guidance for clinicians with respect to exercise for people living with cancer in active and post treatment. It focuses on the benefits of specific types of exercise, pre-screening requirements for new referrals, safety concerns, and delivery models.Methods Using the pebc’s standardized approach, medline and embase were systematically searched for existing guidelines, systematic reviews, and primary literature.Results The search identified two guidelines, eighteen systematic reviews, and twenty-nine randomized controlled trials with relevance to the topic. The present review provides conclusions about the duration, frequency, and intensity of exercise appropriate for people living with cancer.Conclusions The evidence shows that exercise is safe and provides benefit in quality of life and in muscular and aerobic fitness for people with cancer both during and after treatment. The evidence is sufficient to support the promotion of exercise for adults with cancer, and some evidence supports the promotion of exercise in group or supervised settings and for a long period of time to improve quality of life and muscular and aerobic fitness. Exercise at moderate intensities could also be sustainable for longer periods and could encourage exercise to be continued over an individual’s lifetime. It is important that a pre-screening assessment be conducted to evaluate the effects of disease, treatments, and comorbidities.

show abstract

A Multicentre Year-long Randomised Controlled Trial of Exercise Training Targeting Physical Functioning in Men with Prostate Cancer Previously Treated with Androgen Suppression and Radiation from TROG 03.04 RADAR

Cited by 186 publications

References 26 publications

Exercise for People with Cancer: A Clinical Practice Guideline

Exercise for People with Cancer: A Clinical Practice Guideline

Enhancing Survivorship Care Planning for Patients With Localized Prostate Cancer Using a Couple-Focused mHealth Symptom Self-Management Program: Protocol for a Feasibility Study (Preprint)

Exercise for people with cancer: a systematic review

Contact Info

Product

Resources

About