A multichannel electrochemical detector coupled with an ELISA microtiter plate for the immunoassay of 2,4-dichlorophenoxyacetic acid

Deng, Anping; Yang, Hong

doi:10.1016/j.snb.2006.12.023

Cited by 36 publications

(18 citation statements)

References 34 publications

(44 reference statements)

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“…The detection limit for free 2,4-D in water was 0.1 ng/mL. A similar immunosensor coupled with an ELISA microtiter plate was also reported (Deng and Yang, 2007), and the detection limit of 0.072 ng/mL was achieved. The advantages of the presented electrochemical detector were high stability and sample throughput, low detection limit, the ability to be repeatedly used, and no need for regeneration.…”

Section: Amperometric Methodsmentioning

confidence: 60%

Immunosensors for detection of pesticide residues

Jiang

et al. 2008

Biosensors and Bioelectronics

211

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Section: Amperometric Methodsmentioning

confidence: 60%

Immunosensors for detection of pesticide residues

Jiang

et al. 2008

Biosensors and Bioelectronics

211

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“…During recent years new products based on the use of screen printed electrodes have made the use of such electrode material even more attractive. A disposable multichannel immunochemical sensor based on the array of eight working electrodes (gold) and a silver reference electrode printed on a ceramic substrate was, for example, recently developed [32,33]. A novel analytical immunosensor array, which combines the ease of use of the spectrophotometric microplate and the high sensitivity of the electrochemical transducer, has also recently been proposed.…”

Section: Electrochemical Immunosensorsmentioning

confidence: 99%

“…Deng et al [33] proposed an array immunosensor (MED) for simultaneous analysis of several water samples in order to monitor for 2,4-D contamination. A direct competitive immunoassay (Fig.…”

Section: Pesticides 2161 24-dichlorophenoxyacetic Acid 24-mentioning

confidence: 99%

A review on novel developments and applications of immunosensors in food analysis

Ricci

Volpe

Micheli

et al. 2007

Analytica Chimica Acta

314

138

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“…With the emergence of nanostructured materials that enable nanoscale biomolecule confinement, a new class of ultrasensitive portable diagnostics tools has been developed for clinical health care applications. 1,2 However, identifying and matching new materials and technologies for a specific application have been the real challenge in designing and prototyping cost-effective, lab-on-a-chip-based diagnostics platforms. This research succeeds in demonstrating a potentially disruptive technology with the use of iridium oxide (IrOx) nanowires toward ''real-time'' point-of-care testing.…”

Section: Introductionmentioning

confidence: 99%

Iridium Oxide Nanomonitors for Real-Time Health Monitoring Systems

Venkatraman

Zhang²,

Evans³

et al. 2009

JALA: Journal of the Association for Laboratory Automation

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A n innovative lab-on-a-chip device based on iridium oxide (IrOx) nanowires was designed, fabricated, and developed for real-time ''point-of-care'' diagnostics. The turnaround time in detection and the need for expensive equipment for analysis have considverably limited rapid and ''point-of-care'' diagnosis. This research demonstrates the potential of IrOx nanowires toward early disease diagnosis by detecting proteins that are disease markers. The device designed is based on electrical detection of protein biomarkers wherein a single capture immunoassay is built onto a vertically aligned IrOx nanowire platform. Detection of two inflammatory proteins, C-reactive protein (CRP) and myeloperoxidase (MPO) (Calbiochem, La Jolla, CA), that are biomarkers of cardiovascular diseases is demonstrated individually and concurrently. The performance metrics of the device in response to the two biomarkers in pure form and in serum samples were evaluated and compared with standard enzyme-linked immunosorbent assay (ELISA). The methodology that has been adopted is based on measuring real-time impedance changes because of the protein binding event through electrochemical impedance spectroscopy and calibrating its change in magnitude with concentration of proteins. We have demonstrated limit of detection up to 500 pg/mL for protein MPO and 1 ng/mL for CRP with cross-reactivity of less than 8% of selective binding of these two inflammatory biomarkers.

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A multichannel electrochemical detector coupled with an ELISA microtiter plate for the immunoassay of 2,4-dichlorophenoxyacetic acid

Cited by 36 publications

References 34 publications

Immunosensors for detection of pesticide residues

Immunosensors for detection of pesticide residues

A review on novel developments and applications of immunosensors in food analysis

Iridium Oxide Nanomonitors for Real-Time Health Monitoring Systems

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