A multidisciplinary approach to accidental inhalational ammonia injury: A case report

Pangeni, Raju; Timilsina, Bibek; Oli, Prakash Raj; Khadka, Sulochana; Regmi, Pradeep Raj

doi:10.1016/j.amsu.2022.104741

Cited by 10 publications

(4 citation statements)

References 8 publications

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“…Inhaled ammonia is another known respiratory irritant, capable of causing both upper and lower airway irritation via liquefactive necrosis. Interestingly, a prior case report involving an otherwise healthy 22‐year‐old male with accidental occupational exposure to aerosolized ammonia demonstrated a correlation between the respiratory toxicity of this agent and the development of pneumothorax in that patient 14 …”

Section: Discussionmentioning

confidence: 99%

“…Interestingly, a prior case report involving an otherwise healthy 22-year-old male with accidental occu-pational exposure to aerosolized ammonia demonstrated a correlation between the respiratory toxicity of this agent and the development of pneumothorax in that patient. 14 One hypothesis for the occurrence of pneumothorax secondary to the inhalation of 4-nitrophenyl chloroformate is the destabilization of surfactant caused by this substance. Importantly, there was no nasal, oral, tracheal, and laryngeal irritation in this case, suggesting that the chemical toxic metabolite is unlikely to be water soluble.…”

Section: Discussionmentioning

confidence: 99%

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Pneumothorax associated with accidental 4‐nitrophenyl chlonoformate inhalation in an academic chemistry lab

Imler

Martel

2023

JACEP Open

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Pneumothorax associated with accidental 4‐nitrophenyl chlonoformate inhalation in an academic chemistry lab

Imler

Martel

2023

JACEP Open

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“…Formaldehyde, found in building materials, tobacco smoke, and various household products, causes eye, nose, and throat irritation and is a known carcinogen. Ammonia (NH3), released from cleaning products, textiles, and plastics, causes respiratory irritation, coughing, and throat irritation [23].…”

Section: Indoor and Outdoor Toxic Gasesmentioning

confidence: 99%

Integrated Photonic Sensors for The Detection of Toxic Gases - A Review

Butt,

Piramidowicz

2024

Preprint

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Gas sensing is crucial for detecting hazardous gases in industrial environments, ensuring safety and preventing accidents. Additionally, it plays a vital role in environmental monitoring and control, helping to mitigate pollution and protect public health. Integrated photonic gas sensors are important due to their high sensitivity, rapid response time, and compact size, enabling precise recognition of gas concentrations in real-time. These sensors leverage photonic technologies, such as waveguides and resonators, to enhance performance over traditional gas sensors. Advancements in materials and fabrication techniques could further improve their efficiency, making them invaluable for environmental monitoring, industrial safety, and healthcare diagnostics. In this review, we delved into photonic gas sensors that operate based on the principles of evanescent field absorption (EFA) and wavelength interrogation methods. These advanced sensing mechanisms allow for highly sensitive and selective gas detection, leveraging the interplay of light with gas molecules to produce precise measurements.

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“…Upon release, ammonia reacts with water to form ammonium hydroxide which irritates the mucosa and at high concentrations causes severe upper airways irritation and respiratory failure within two to five minutes of exposure (Saeed, Boyer et al 2018). Tissue damage occurs through exothermic reactions with body tissues, causing alkali skin burns and liquefactive necrosis (Pangeni, Timilsina et al 2022). In some cases, survivors may develop complications such as bronchiectasis, AHR, BO, COPD, ILD, and end-stage disease that requires lung transplantation.…”

Section: Irritantsammoniamentioning

confidence: 99%