BACKGROUND
Atrial fibrillation (AF) occurs in many clinical contexts and is diagnosed and treated by clinicians across many specialties, which has been associated with treatment variation.
OBJECTIVES
We evaluated the association of treating specialty with AF outcomes among patients with newly-diagnosed AF.
METHODS
Using complete data of the TREAT-AF (The Retrospective Evaluation and Assessment of Therapies in AF) study from the Veterans Health Administration, we identified patients with newly diagnosed, nonvalvular AF between 2004-2012 and at least one outpatient encounter with primary care or cardiology within 90 days of AF diagnosis. Cox proportional hazards regression was used to evaluate association between treating specialty and AF outcomes.
RESULTS
Among 184,161 patients with newly-diagnosed AF (age 70±11; 1.7% women; CHADS-VASc 2.6±1.7), 40% received cardiology care and 60% received primary care only. After adjustment for covariates, cardiology care was associated with reductions in stroke (HR 0.91, 95% CI 0.86-0.96, p <0.001) and death (HR 0.89; 95% CI 0.88-0.91; p <0.0001) and increases in AF/SVT (HR 1.38; 95% CI 1.35-1.42; p <0.0001) and MI (HR 1.03; 95% CI 1.00-1.05; p <0.04). The propensity matched cohort had similar results. In mediation analysis, oral anticoagulation (OAC) prescription within 90 days of diagnosis may have mediated reductions in stroke but did not mediate reductions in survival.
CONCLUSIONS
In patients with newly-diagnosed AF, cardiology care was associated with improved outcomes, potentially mediated by early OAC prescription. Although hypothesis-generating, these data warrant serious consideration and study of health care system interventions at the time of new AF diagnosis.