A Multifrequency Water-filled Waveguide Application Thermal Dosimetry In Vivo (Short Paper)

Lovisolo, Giorgio A.; Adami, Maurice Zarb; Arcangeli, Giorgio; Borrani, A.

doi:10.1109/tmtt.1984.1132799

Cited by 26 publications

(6 citation statements)

References 4 publications

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“…In each case the power density is approximately 60% of the SAR at the surface of the cylinder. Note that in spite of the varying number and sizes of the aperture used, the power density is predicted to be constant at the center of the cylinder for this model [Lumori, 1988;Wait and Lumori, 1986]. In the case of four apertures, however, extra (spurious) hot spots are unavoidable when focusing is desired at some point other than the center of the model, as indicated in Figure 3a.…”

Section: Discussionmentioning

confidence: 85%

“…The analysis, which follows and extends that of Wait [1984Wait [ , 1985Wait [ , 1987aWait [ , b, 1988, is performed for the time harmonic factor exp froot), where a, is the angular frequency. An expression for the electric field Ez( p, ok) at any interior point (p • a) can be derived as the sum of N aperture field contributions, and the field contribution due to the nth aperture is [Wait and Lumori, 1986;Lumori, 1988…”

Section: Discussionmentioning

confidence: 99%

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Power deposition and focusing in a lossy cylinder by a concentric phased array

Lumori¹,

Wait²,

Cetas³

1989

Radio Science

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We present an analysis of phased array applicators for heating of torso, limbs, and neck. A homogeneous cylindrical model is adopted for the calculations. Four-, eight-, and 16-horn apertures are considered. Focusing of power is demonstrated for an operation frequency of 915 MHz in a cylindrical phantom of radius 5.2 cm, with a conductivity of 1.28 S/m and a relative permittivity of 51. Experimental verification is shown for the case with four-horn applicators. We thus demonstrate that by controlling the relative phases and amplitudes of the aperture sources, it is possible to focus electromagnetic power at desired locations such as tumors. LUMORI

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Section: Discussionmentioning

confidence: 85%

Section: Discussionmentioning

confidence: 99%

Power deposition and focusing in a lossy cylinder by a concentric phased array

Lumori¹,

Wait²,

Cetas³

1989

Radio Science

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“…The measurements were processed in a network analyzer (Hewlett Packard Model 8754A) for phase, relative electric (a) (b) Figure 2. Schematics of (a) SMA (Italian Company) multifrequency water-loaded waveguide applicator with a circular aperture [4,13] and (b) current sheet applicator (CSA): Inductive microwave aperture antenna with a Teflon aperture for interface matching [5]. The parametric values in (13) and (14) are unique characteristics of the applicator type; they are complex source points from which electromagnetic waves emanate [2,4,5].…”

Section: Materials and Experimental Methodsmentioning

confidence: 99%

“…• The experimental procedure used in conjunction with the GBM to determine the source parameters in (13) and (14) accounted for the fields in the aperture-bolus-air-muscle interfaces peculiar to the SMA, CSA or any other applicator set-up for treatment planning in electromagnetic hyperthermia. • In Fig.…”

Section: Materials and Experimental Methodsmentioning

confidence: 99%

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Gaussian Beam Modeling of Sar Enhancement in Paraxial and Non-Paraxial Regions of Biological Tissues

Lumori¹

2010

PIER M

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Abstract-A polarized 3D-electromagnetic wave propagating from an aperture source into a lossy medium can be modeled by an astigmatic Gaussian beam model (GBM) of complex source coefficients that characterize a radiating antenna uniquely. The source coefficients are determined numerically from phantom experiments, and then used in simulations of specific absorption rates (SAR), in both homogeneous and layered biological media, resulting in good agreement with experimental data. This paper shows that for an x-polarized E-field the GBM simulations of SAR enhancement or focus in the axial, z-directed, paraxial region are accurate, but approximate in the transverse, y-directed, non-paraxial regions due to a focal shift.

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Radiotherapy and hyperthermia. Analysis of clinical results and identification of prognostic variables

Arcangeli¹,

Benassi

Cividalli

et al. 1987

Cancer

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Site-and tumor-specific data obtained from two groups of patients with head and neck and melanoma lesions, respectively, showed that both immediate response and response duration were enhanced by the addition of heat. Two important variables, however, such as tumor volume and "isoeffect thermal dose" appeared to influence local tumor control. The volume effect was less pronounced in the lesions treated with radiotherapy plus heat than in those treated with radiotherapy alone, suggesting that the addition of heat was more damaging to the large than to the small lesions. Furthermore, a striking isoeffect thermal dose-response relationship was shown in head and neck lesions. Those data were collected and used to design a mathematical model relating the probability of local control to clinical and treatment variables. The analysis shows that, by using the same radiation parameters, the probability of local tumor control is a function of both "isoeffect thermal dose" and tumor volume. Cancer 60:950-956,1987. HE CLINICAL EXPERIENCE accumulated in recent T years has clearly shown the potential of using hy-perthermia in addition to radi~therapy.'-~ Despite the inhomogeneity of patient population under treatment with regards to tumor size, location and histology, the results of all published studies have been surprisingly consistent in showing a constant therapeutic benefit of the combined modality over radiation alone.2 However, the information on specific tumor site and histology as well as the duration of the heat improved radiation response is limited5-' and deserves more careful investigation. The aim of this report is to discuss the results of the various treatment schedules, and to examine the mechanisms and factors affecting tumor response in general, as well as to provide site-and tumor-specific data with respect to initial response and response duration. Materials and Methods This study comprised 38 patients with 81 multiple neck node metastases from squamous cell carcinoma of

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A Multifrequency Water-filled Waveguide Application Thermal Dosimetry In Vivo (Short Paper)

Cited by 26 publications

References 4 publications

Power deposition and focusing in a lossy cylinder by a concentric phased array

Power deposition and focusing in a lossy cylinder by a concentric phased array

Gaussian Beam Modeling of Sar Enhancement in Paraxial and Non-Paraxial Regions of Biological Tissues

Radiotherapy and hyperthermia. Analysis of clinical results and identification of prognostic variables

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