Regional climate model has been widely used to simulate terrestrial water cycles, but its simulations used in the long-term agriculture drought reconstruction have not been investigated in China. This study presents an analysis of soil moisture (SM) drought in China during 1911-2010 on the basis of the simulations from the Weather Research and Forecasting (WRF) model driven by two twentieth century reanalysis products. Comparisons of modelled SM with station observations indicate that WRF has certain capability in reproducing its magnitudes and temporal variabilities. Model performance are greatly impacted by lateral boundary conditions. The average SM derived from two experiments is closer to observations than the individual one and thus they are then applied in drought investigation. During the study period, SM shows a wetting tendency from northwestern to central eastern China, while it displays a drying tendency in the northeast, western Tibetan Plateau, and part of southeastern China. The spatial pattern of number drought events resembles that of annual precipitation, showing an increasing tendency from northwestern (arid) to southeastern (humid) regions. In arid regions, drought events are generally prolonged and frequent but less severe. In humid regions, in contrast, drought events usually persist less than 6 months and are less frequent but relatively severe. During the examined 100-year period, roughly 28.4, 28.9 and 38.4% of land areas in China show significant trends for duration, severity, and frequency, respectively (p > .8). Both drought duration and severity show decreasing tendencies in vast regions, and the land areas showing increased drought frequency is slightly less than that of areas showing its decreased tendency. This study is a first attempt to apply regional climate modelling to investigate a centennial long SM change in China and presents a new way to explore long-term drought characteristics and their changes.