A Naphthol and Nitroaniline‐Based Dual‐target Chemosensorfor Fluorometric Sensing of Al³⁺ and Colorimetric Sensing of Fe³⁺

Abstract

A naphthol and nitro‐aniline‐based fluorometric and colorimetric chemosensor BHMN, 1,1‐bis(2‐(((E)‐(2‐hydroxy naphthalene‐1‐yl)methylene)amino)ethyl)‐3‐(4‐nitrophenyl)thiourea, was synthesized. Sensor BHMN detected Al3+ with fluorescence turn‐on and Fe3+ via color variation of colorless to purple. Binding ratios of BHMN to Al3+ and Fe3+ turned out to be 1 : 1. Detection limits for Al3+ and Fe3+ by BHMN were analyzed to be 8.22 μM and 3.10 μM. Additionally, the naked‐eye test strip was applied for sensing Fe3+ and showed that BHMN could effectively discriminate Fe3+ from Fe2+ and other cations. The binding mechanisms of BHMN to Al3+ and Fe3+ were identified by ESI‐mass, Job plot, NMR titration, and DFT calculations.

An AIE active fluorescence sensor for measuring Fe3+ in aqueous media and an iron deficiency anemia drug

“…LOD = 1.3 µM was considerably lower than the limit value for the drinking water given by the U.S. Environmental Protection Agency (5.4 µM) and the values found in many studies in the literature. [45][46][47][48][49][50] Also, the binding stoichiometry between TPE-TAP and Fe 3+ ions was discussed with Job's plot. A point in the 0.4 mole fractions indicated a 2 : 1 binding interaction between the sensor TPE-TAP and Fe 3+ ions (Fig.…”