A Narrative study about the role of Viola odorata as traditional medicinal plant in management of respiratory problems

Mahboubi, Mohaddese; Kashani, Leila Mohammad Taghizadeh

doi:10.1016/j.aimed.2017.12.003

Cited by 24 publications

(16 citation statements)

References 22 publications

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“…Furthermore, blocking voltage-dependent Ca 2+ channels or suppressing Ca 2+ release from the sarcoplasmic reticulum in PE-induced or spontaneously contracting isolated rabbit tissue preparations was also confirmed in a recent study [90]. Importantly, a phytochemical screening of V. odorata extracts and essential oils revealed the presence of a wide range of bioactive compounds [90,91], making it an attractive plant for further cardiovascular investigations.…”

Section: Discussionmentioning

confidence: 71%

Antihypertensive Indigenous Lebanese Plants: Ethnopharmacology and a Clinical Trial

et al. 2019

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Hypertension is highly prevalent among the Lebanese adult population and is indeed the major cause of mortality in Lebanon. Traditional use of antihypertensive medicinal plants has long been practiced. The aim of this study is to document this traditional knowledge and clinically test the antihypertensive capacity of three of the most commonly used wild plant species Mentha longifolia, Viola odorata and Urtica dioica. Ethno-pharmacological data was collected by personal interviews with herbalists and traditional healers using a semi structured survey questionnaire and assessing relative frequency of citation (RFC). The clinical study was conducted by a randomized, blind, placebo-controlled trial in 29 subjects with mild hypertension distributed in four groups, three plant extract treatments and one placebo. Systolic (SBP) and diastolic blood pressures (DBP) as well as mean arterial blood pressures (MAP) were monitored at weeks 4, 8, 12 and 16 during the treatment with 300 mL/day of plant extract. Results showed that M. longifolia, U. dioica and V. odorata exhibited the highest values of RCF (0.95) followed by Allium ampeloprasum (0.94), Apium graveolens (0.92) and Crataegus azarolus (0.90). The clinical trial revealed dose- and duration-dependent significant reductions in SBP, DBP and MAP of subjects treated with M. longifolia, U. dioica or V. odorata. Our findings indicate that extracts of these plants present an effective, safe and promising potential as a phyto-therapuetical approach for the treatment of mild hypertension. More research on the phytochemistry, pharmacological effects and the underlying mechanisms is necessary.

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Section: Discussionmentioning

confidence: 71%

Antihypertensive Indigenous Lebanese Plants: Ethnopharmacology and a Clinical Trial

et al. 2019

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“…The results can be attributed to certain factors, such as drastic weather change and a high proportion of moisture, cold, germs and spores, which may lead to abnormalities in the respiratory tract [ 181 , 240 , 241 , 242 ]. The plants that were employed mainly for the treatment of respiratory ailments were D. costus , C. impatiens and C. domestica, and were supported by the literature [ 180 ]. The ethnobotanical studies of D. costus highlighted that this taxon employed in respiratory diseases such as asthma and bronchitis [ 176 , 243 , 244 , 245 ].…”

Section: Discussionmentioning

confidence: 99%

Ethnobotany of the Himalayas: Safeguarding Medical Practices and Traditional Uses of Kashmir Regions

Bhat

Singh

Surmal

et al. 2021

Biology

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The present study was carried out to enlist the medicinal plants used by the local inhabitants of developing countries such as India, and the district of Kupwara of the Kashmir Himalaya has been targeted. Our research is one of the first study focusing on the statistical evaluation of the cross-cultural analysis between three different communities i.e., Dard, Kashmiri and Gujjar, of the study area. Sampling was carried out in eight villages in 2017 to 2020, and data were collected from 102 informants based on walking transects, to collect plant specimens, and semi-structured interviews. The medical usages of all collected taxa were grouped into 15 disease categories and 81 biomedical ailments. In this study, we documented around 107 plant taxa belonging to 52 families from the local inhabitants of the Kashmir Himalaya, which regulate the livelihood of the people and support cultural ecosystem services. Asteraceae, Rosaceae, Lamiaceae, Malvaceae, Ranunculaceae, Poaceae, Solanaceae, Polygonaceae, Plantaginaceae and Brassicaceae are the top most dominant families. Herbaceous groups of plants were more common than trees and shrubs, and 71.96% of herb taxa were employed as medicine. Liliaceae, Caprifoliaceae and Portulacaceae (FUV = 0.24 each) have the highest family use value (FUV). The most prominent family was Asteraceae (seven genera, nine taxa), followed by Rosaceae and Lamiaceae (six genera, six taxa each). Persicaria Mill., Rheum L., Aconitum L. and Artemisia L. were prominent genera. Valeriana jatamansi Jones ex Roxb. (47UR), Fritillaria cirrhosa D. Don (45UR), Arisaema jacquemontii Blume (37UR), Asparagus racemosus Willd. (36UR) and Rumex acetosa L. (35UR) were the most important plant taxa with reference to use-reports. The ethnomedicinal applications of Aesculus indica Wall. ex Cambess., Solanum pseudocapsicum L., Ranunculus hirtellus Royle and Cormus domestica (L.) Spach plant taxa are reported here for the first time from the Himalayan Kashmiri people. We recommend further research on ethnopharmacological application of these newly recorded ethnobotanical plants. The medical usage of the plant was limited to different parts of the plant. In terms of the usage percentage, whole plant (26.17%), leaves (24.30%) and roots (19.63%) were found to have the highest utilization. The powder form (40.19%) was the most frequently employed method of drug/medicine preparation, followed by the utilization of extracted juice and/or other extracts (22.43%). The ICF values range from 0.85 to 1.00. Their use to remedy parasitic problems (PAR) and insect bites (IB) (ICF = 1.0 each) had the maximum consensus mentioned by the informants, although the number of taxa employed under this category was very limited. The different plant taxa used for the treatment of the gastrointestinal problems (GAS) was the most prominent disease category (262 URs, 16.19%, 25 taxa, ICF = 0.90). About 65% of the plant taxa studied is indigenous to the Asia or Himalayan regions, and around 35% is found to be exotic in nature. A strong positive correlation was found between age, gender, educational qualification and medicinal plant knowledge. No significant association was between people of different communities interviewed in terms of medical knowledge of the plants, p = 0.347 (>0.05) and χ2 = 2.120. No significant difference was found between the number of species documented concerning gender as p = 0.347 (>0.05) and χ2 =0.885. This study provides the comprehensive status of ethnomedicinal knowledge among three different communities of the study area. This study provided an impetus in discovering the baseline primary data for molecules which would help in drug discovery and management of various diseases, apart from conserving the genepool of plants in the investigated area.

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“…On the other hand, recent studies have confirmed the anti-proliferative effects of several plants such as Althaea officinalis (32,33) , Glycyrrhiza glabra L. (34,35,36) , Echium amoenum (37,38,39) , Origanum majorana (40,41) and Viola odorata (42,43,44) on viruses. Furthermore, these studies reported the antioxidant properties of Althaea officinalis (32,33) , Glycyrrhiza glabra (9,34,35,36) , Matricaria chamomilla (45,46,47) and mint (48) , the repairing effect of Althaea officinalis (32,33) and Malva sylvestris (49,50,51) and also the positive effect of Matricaria chamomilla (45,46,47) and cheese in strengthening the immune system.…”

Section: • Strengthen the Lungs And Other Involved Organsmentioning

confidence: 94%

“…These plants also show their therapeutic effects by improving endogenous antioxidant enzymes, regulation of signaling pathways and related kinases, as well as inhibiting of apoptotic pathways and regenerating of damaged cells or tissues. (32)(33)(34)(35)(36)(37)(38)(39)(40)(41)(42)(43)(44)(45)(46)(47)(48)(49)(50)(51)…”

Section: • Strengthen the Lungs And Other Involved Organsmentioning

confidence: 99%

Identifying Appropriate Therapeutic Methods in Covid-19 Originated from Persian Medicine: A Review Article

Maryam Monfared,

Mahdieh Eftekhari,

Samin Amini

et al. 2021

Indian Journal of Forensic Medicine & Toxicology

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Objectives: COVID-19, a novel Coronavirus from same family as SARS-CoV-2 is a highly contagious virus. It is transmitted mainly from upper respiratory system and affects important organs, like heart and lungs. The aim of this study is identifying appropriate therapeutic methods originated from persian medicine. Materials and Methods: This study has been designed from the viewpoints of traditional and modern medicine. Considering modern medicine, we searched valid database by searching key words "SARS-Cov-2" and "COVID-19". For traditional medicine, we searched reliable traditional medicine like the "Canon of Medicine" by "Avicenna", the Exir-e Aazam and Zakhira-I Kharazm Shahi. Patients were evaluated according to their symptoms and categorized based on traditional medicine. Physiopathology and management of the disease, including prevention and treatment were studied. Results: The principle underlying mechanism seems to be warm and dry dystemperament that affects different organs and causes various adverse effects which are higher than warm and dry dystemperament, but less than the presence of virus. Our traditional Iranian medicine findings are validated by the modern medicine. Conclusion: Based on symptoms, the equivalent of this disease was examined from the viewpoint of traditional medicine. Then, physiopathology and management of this disease were presented in five levels, including one stage of prevention and four stages of treatment, and finally, the treatment recommendations of Iranian traditional medicine were approved with new research results.

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A Narrative study about the role of Viola odorata as traditional medicinal plant in management of respiratory problems

Cited by 24 publications

References 22 publications

Antihypertensive Indigenous Lebanese Plants: Ethnopharmacology and a Clinical Trial

Antihypertensive Indigenous Lebanese Plants: Ethnopharmacology and a Clinical Trial

Ethnobotany of the Himalayas: Safeguarding Medical Practices and Traditional Uses of Kashmir Regions

Identifying Appropriate Therapeutic Methods in Covid-19 Originated from Persian Medicine: A Review Article

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