A Narrowband Pulse-Echo Technique for In Vivo Ultrasonic Attenuation Estimation

Ophir, Jonathan; McWhirt, R. E.; Maklad, Nabil F.; Jaeger, Paul

doi:10.1109/tbme.1985.325530

Cited by 28 publications

(12 citation statements)

References 15 publications

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“…33 This observation had been noted in previous investigations as well. [34][35][36] In the work by Yao, Zagzebski, and Madsen, the statistical uncertainty in the backscatter coefficient was found to have two sources: One source depends on the number of acoustic lines ͑width of the region-of-interest͒ and on the number of independent samples along each line ͑length of the region-of-interest͒ as in the case for the attenuation coefficient. The second source of uncertainty arises from the dependence of backscatter coefficient measurements on overlying attenuation and is directly related to the statistical uncertainty in the attenuation estimation.…”

Section: Discussionmentioning

confidence: 99%

Effects of region-of-interest length on estimates of myocardial ultrasonic attenuation and backscatter

et al. 2005

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Measurements of tissue properties using an image-based technique that makes use of an external reference may have the potential for practical clinical implementation in echocardiography. The objective of this study was to quantify the ability of this technique to distinguish myocardial attenuation and backscatter properties for specific lengths of the region-of-interest (ROI). We chose to exploit the anisotropic properties of the myocardium as a model for distinguishing tissue with different acoustic properties. Excised lateral wall segments from seven healthy adult sheep hearts were imaged using a commercially available (Philips/ATL) clinical scanner operating in the fundamental imaging mode with a linear array (L 7-4). Statistical and receiver operating characteristic (ROC) analyses were used to evaluate the ability of the video signal analysis method to differentiate midmyocardial from subendocardial regions based on measurements of the acoustic properties for specific lengths of the ROI. Results demonstrate that the ability to distinguish tissue properties increases with ROI length for both slope of attenuation and backscatter coefficient measurements. Statistically significant differences were observed for measurements utilizing the ROI lengths as short as 0.4 cm with corresponding progressively increasing areas under the ROC curves for increasing ROI lengths. [NIH R37 HL40302]

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Section: Discussionmentioning

confidence: 99%

Effects of region-of-interest length on estimates of myocardial ultrasonic attenuation and backscatter

et al. 2005

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“…Our previous study 7 showed that the attenuation coefficient values obtained with the novel method were significantly greater than those obtained with the SS method in fatty livers, but no significant differences were seen in normal and cirrhotic livers. Many reports [16][17][18][19][20] indicate that a power law function of the type α(f ) = α 0 f n describes the frequency dependence rather well. As in most reports, a linear frequency dependence of attenuation, that is, n = 1, was assumed in this study.…”

Section: Discussionmentioning

confidence: 99%

Attenuation Coefficient Measurement in the Thyroid

Fujii

Taniguchi

Itoh

et al. 2003

Journal of Ultrasound in Medicine

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Objective. To assess the feasibility of a novel method of measuring the attenuation coefficient in the thyroid, which offers less variability of results than the conventional method. Methods. In our new method, the attenuation coefficient was evaluated on the basis of the following equation with sound field correction: . In our system, the attenuation coefficient was also evaluated by the spectral shift central frequency method at the same time. In this study, we used 32 cases of normal thyroid, 26 cases of Graves disease, and 11 cases of Hashimoto thyroiditis in the system. Results. With this novel method, attenuation coefficient values of the thyroid (mean ± SD) were 1.50 ± 0.26 dB · cm -1 · MHz -1 in the normal group, 0.91 ± 0.23 dB · cm -1 · MHz -1 in the Graves disease group, and 1.10 ± 0.27 dB · cm -1 · MHz -1 in the Hashimoto thyroiditis group. The novel method recorded a statistically significant difference between normal and diseased thyroids (P < .0001) and between Graves disease and Hashimoto thyroiditis groups (P = .0035). Statistical variation of the attenuation coefficient values obtained using the novel method was much smaller than that of those obtained by the spectral shift central frequency method in every group. Conclusions. This new method is considered usable for evaluating the attenuation coefficient of the thyroid in vivo.

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“…However, they have been used to study soft tissues. For example, backscatter difference techniques were used to estimate the ultrasonic attenuation of human liver in vivo (Kuc, 1980;Fink et al, 1983;Ophir et al, 1984;Ophir et al, 1985). The goal of the present study is to investigate the utility of backscatter difference techniques for ultrasonic bone assessment.…”

Section: Introductionmentioning

confidence: 99%

A backscatter difference technique for ultrasonic bone assessment

Hoffmeister

Wilson

Gilbert

et al. 2012

The Journal of the Acoustical Society of America

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Ultrasonic backscatter techniques may offer a useful approach for detecting changes in cancellous bone caused by osteoporosis and other diseases. The goal of this study was to investigate the utility of a backscatter difference technique for ultrasonic bone assessment. Measurements were performed on 22 cube-shaped specimens of human cancellous bone using four broadband transducers with center frequencies 2.25, 5, 7.5, and 10 MHz. The backscatter difference spectrum D(f) was obtained by subtracting power spectra (in dB) from two different portions of the same backscatter signal. D(f) was found to be a monotonically increasing, quasi-linear function of frequency when averaged over multiple measurement sites on multiple specimens. The frequency slope of D(f) demonstrated weak to moderate correlations with specimen density (R ¼ 0.21-0.80). The frequency averaged mean of D(f) demonstrated moderate to good correlations with density (R ¼ 0.70-0.95). These results suggest that parameters based on the frequency averaged mean of the backscatter difference spectrum may be useful for bone assessment purposes.

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A Narrowband Pulse-Echo Technique for In Vivo Ultrasonic Attenuation Estimation

Cited by 28 publications

References 15 publications

Effects of region-of-interest length on estimates of myocardial ultrasonic attenuation and backscatter

Effects of region-of-interest length on estimates of myocardial ultrasonic attenuation and backscatter

Attenuation Coefficient Measurement in the Thyroid

A backscatter difference technique for ultrasonic bone assessment

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