The nasopalatine region is composed of structures such as the vomeronasal organ and
nasopalatine duct. The nasopalatine duct may provide the communication of the mouth
to the nasal cavity in human fetuses and can be obliterated in an adult human.
Knowledge on the development of the nasopalatine region and nasopalatine duct in
humans is necessary for understanding the morphology and etiopathogenesis of lesions
that occur in this region.Objective:The aim of the present study was to describe the morphological aspects of the
nasopalatine region in human fetuses and correlate these aspects with the
development of pathologies in this region. Material and Methods:Five human fetuses with no facial or palatine abnormalities were used for the
acquisition of specimens from the nasopalatine region. After demineralization, the
specimens were histologically processed. Histological cuts were stained with
methylene blue to orient the cutting plane and hematoxylin-eosin for the
descriptive histological analysis. Results:The age of the fetuses was 8.00, 8.25, 9.00 and 9.25 weeks, and it was not
possible to determine the age in the last one. The incisive canal was observed in
all specimens as an opening delimited laterally by the periosteum and connecting
oral and nasal cavity. The nasopalatine duct is an epithelial structure with the
greatest morphological variation, with either unilateral or bilateral occurrence
and total patent, partial patent and islet forms. The vomeronasal organ is a
bilateral epithelized structure located alongside the nasal septum above the
incisive canal in all the fetuses. Conclusions:The incisive canal, nasopalatine duct and vomeronasal organ are distinct anatomic
structures. The development of nasopalatine duct cysts may occur in all forms of
the nasopalatine duct.