Gynecologic cancer confers a large burden among women in the United States. Several evidence-based interventions are available to reduce the incidence, morbidity, and mortality from these cancers. The National Comprehensive Cancer Control Program (NCCCP) is uniquely positioned to implement these interventions in the US population. This review discusses progress and future directions for the NCCCP in preventing and controlling gynecologic cancer.
Gynecologic Cancer in the United StatesA pproximately 84,000 new cases are diagnosed and about 28,000 deaths occur each year from gynecologic cancer among women in the United States.1 Five cancers account for the vast majority of gynecologic cancer cases: cervical, ovarian, uterine, vaginal, and vulvar. Uterine cancer diagnoses are common; uterine is the fourth highest incident cancer among women in the US after breast, lung, and colorectal cancers.1 Ovarian cancer is the eighth most common cancer diagnosed; however, it is the fifth leading cause of cancer death among US women. Cervical, vaginal, and vulvar cancers are relatively less common than uterine and ovarian cancers; however, diagnoses and deaths from these three cancers still number in the thousands each year.1 The economic burden of gynecologic cancer is substantial in the US. In a single state (California) during a 1-year period, cervical, ovarian, and uterine cancers accounted for $624 million in direct health care costs and lost productivity due to premature death.2 Ovarian cancer was the most costly ($292 million), followed by cervical cancer ($206 million) and uterine cancer ($126 million).