The innovative psychology, intrapsychic humanism, is applied to formulate guidelines for effectively managing violent symptoms of severely mentally ill clients in residential settings, with the aims of: 1) helping staff reduce client violence; and 2) helping clients regulate their violent behavior. Using intrapsychic humanism, staff can understand, anticipate, and respond therapeutically to client violence. Triggers of violence, such as aversive reactions to pleasure and destructive reactions to real losses are described. Residential program structures that strengthen clients' constructive motives and staff's caregiving motives are outlined.