A neonate with hand, foot, and mouth disease complicated with brainstem encephalitis and pulmonary edema: A complete recovery

Guo, Shijie; Wang, Dongxuan; Dai, Chunlai; Wu, Hui

doi:10.12669/pjms.304.4528

Cited by 5 publications

(4 citation statements)

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“…Two severe cases in newborns were reported in 2014. [ 1 , 2 ] But the epidemiology and clinical impact of HFMD with neonates are still unknown. Here, we present 5 cases with benign illness.…”

Section: Introductionmentioning

confidence: 99%

Case report

Chen

Yang²,

Lian³

et al. 2017

Medicine

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Rationale:Hand, foot and mouth disease (HFMD) is caused by enterovirus. The virus may exist in secretions.Patient concerns:Five neonates had symptoms of fever and maculopapular rashes involving face, trunk, breech, arms, and legs, especially scattering on palms and feet. Blood, oropharyngeal fluid, urine, and cerebrospinal fluid (CSF) samples were collected and detected for further diagnoses with the consent of the infants’ parents. Some of them suffered aseptic meningitis.Diagnoses:They were diagnosed as HFMD with CSF enterovirus positive.Interventions:All of them continued breastfeed. Water bag was used during the pyrogenic stage. Antibiotics were administrated at first and withdrawn as soon as possible.Outcomes:None of them developed into brainstem encephalitis or pulmonary edema and they all recovered well.Lessons:HFMD is more common in neonates than it has been thought. Enterovirus may exist in neonatal CSF and cause CSF cell to increase similar to purulent meningitis. Medical history, physical examination, and CSF enterovirus detection are important in making correct diagnosis. Unlike bacterial infection, HFMD is a self-limited disease. Once HFMD is determined and bacterial infection is ruled out, antibiotics should be avoided.

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Section: Introductionmentioning

confidence: 99%

Case report

Chen

Yang²,

Lian³

et al. 2017

Medicine

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“…Antibiotic was administrated when admitted and stopped when the CSF turned normal and the cultures came out negative. Cranial magnetic resonance imaging (MRI) was normal [17].…”

Section: Case Reportmentioning

confidence: 99%

Exploring the Impact of Hand- Foot Syndrome on Fingerprint Persistence: A Comprehensive Review

Vinchurkar

2024

ACCP

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The hand-foot syndrome, also known as Palmar-Plantar Erythrodysesthesia (PPE), is a dermatological condition associated with certain chemotherapeutic agents. From a forensic perspective, understanding the manifestations of PPE becomes crucial in cases involving drug-related exposures or poisoning. This abstract explores the dermatological aspects of handfoot syndrome, its potential forensic implications, and the importance of recognizing and documenting such findings in medicolegal investigations. Additionally, the abstract discusses the relevance of PPE in establishing a link between a specific chemotherapeutic drug and its adverse effects, aiding forensic experts in determining the cause of morbidity or mortality in relevant cases. Hand-Foot Syndrome (HFS), a dermatological condition commonly associated with chemotherapy, presents a unique avenue for forensic investigation. This study endeavors to unravel the forensic implications of HFS, shedding light on its potential significance in post-mortem examinations. Characterized by erythematous and desquamative changes on the palms and soles, HFS has distinct clinical manifestations that may serve as valuable markers in forensic pathology. Our research employs a comprehensive approach, integrating dermatological analysis with forensic perspectives. Through an extensive review of case studies and medical records, we aim to establish a nuanced understanding of HFS patterns and their correlation with diverse forensic scenarios. By identifying and documenting these distinctive dermatological features, forensic professionals can potentially utilize HFS as an additional tool in their investigative arsenal. Furthermore, this study explores the temporal aspects of HFS progression, seeking to determine the reliability of its manifestation timeline in forensic reconstructions. By elucidating the chronological patterns of HFS development, forensic experts may enhance their ability to establish a timeline of events in cases involving suspicious or unexplained deaths. In conclusion, this research contributes to bridging the gap between dermatology and forensic science, offering insights into the forensic relevance of Hand-Foot Syndrome. The findings presented here aim to empower forensic practitioners with an additional layer of diagnostic precision, ultimately aiding in the pursuit of justice and accurate cause-of-death determinations

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“…Thorough oral prophylaxis was done. Informed consent was obtained from the patient for reporting the case [17].…”

Section: Case Reportmentioning

confidence: 99%

Exploring the Impact of Hand-Foot Syndrome on Fingerprint Persistence: A Comprehensive Review

2024

PDRAJ

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The hand-foot syndrome, also known as Palmar-Plantar Erythrodysesthesia (PPE), is a dermatological condition associated with certain chemotherapeutic agents. From a forensic perspective, understanding the manifestations of PPE becomes crucial in cases involving drug-related exposures or poisoning. This abstract explores the dermatological aspects of handfoot syndrome, its potential forensic implications, and the importance of recognizing and documenting such findings in medico legal investigations. Additionally, the abstract discusses the relevance of PPE in establishing a link between a specific chemotherapeutic drug and its adverse effects, aiding forensic experts in determining the cause of morbidity or mortality in relevant cases. Hand-Foot Syndrome (HFS), a dermatological condition commonly associated with chemotherapy, presents a unique avenue for forensic investigation. This study endeavors to unravel the forensic implications of HFS, shedding light on its potential significance in post-mortem examinations. Characterized by erythematous and desquamative changes on the palms and soles, HFS has distinct clinical manifestations that may serve as valuable markers in forensic pathology. Our research employs a comprehensive approach, integrating dermatological analysis with forensic perspectives. Through an extensive review of case studies and medical records, we aim to establish a nuanced understanding of HFS patterns and their correlation with diverse forensic scenarios. By identifying and documenting these distinctive dermatological features, forensic professionals can potentially utilize HFS as an additional tool in their investigative arsenal. Furthermore, this study explores the temporal aspects of HFS progression, seeking to determine the reliability of its manifestation timeline in forensic reconstructions. By elucidating the chronological patterns of HFS development, forensic experts may enhance their ability to establish a timeline of events in cases involving suspicious or unexplained deaths. In conclusion, this research contributes to bridging the gap between dermatology and forensic science, offering insights into the forensic relevance of Hand-Foot Syndrome. The findings presented here aim to empower forensic practitioners with an additional layer of diagnostic precision, ultimately aiding in the pursuit of justice and accurate cause-of-death determinations.

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A neonate with hand, foot, and mouth disease complicated with brainstem encephalitis and pulmonary edema: A complete recovery

Cited by 5 publications

References 5 publications

Case report

Case report

Exploring the Impact of Hand- Foot Syndrome on Fingerprint Persistence: A Comprehensive Review

Exploring the Impact of Hand-Foot Syndrome on Fingerprint Persistence: A Comprehensive Review

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