As computing and data-driven technologies have improved, the precision of the building thermal control models has been gradually improved, but the use of energy resources to operate them has been also increased. It is imperative to investigate the optimized point of energy use and human comfort for their thermal control strategies. The aim of this research is to find an energy-efficient thermal control model to maintain the constancy of thermal comfort and suppress the increase of energy use in association with precise environmental controls. Based on a cooling and heating air supply model in a simplified building model, a comprehensive energy use pattern is confirmed by adding an adaptive control model that allows indoor thermal comfort to be maintained at a setting level. The adaptive control model utilizing the artificial neural network and the adjustment process of initial settings is proposed to examine its performance in controlling the amount of thermal supply air and its temperature. For the clear comparison between a baseline model and a proposed model, the statistical indices of each thermal dissatisfaction value and the weekly heating energy use are utilized. The results of this research show that the thermal dissatisfaction fluctuation is alleviated by about 22.0~41.0% and the energy efficiency is improved by about 5.1%, respectively. The results provide the effectiveness of the proposed model which can improve both the energy use and thermal comfort in a building space. This advantage can help old thermal systems to improve their usability without replacing any major components.