“…With the rapid development of big data and artificial intelligence, various engineering design optimization problems with unknown large-scale parameters increase exponentially, e.g., Li-ion battery health prediction, 1 offline time-sensitive load scheduling, 2 railway passenger network operation, 3 optimal clustering design, 4 remote sensing images, 5 electronic system design, 6 deep neural networks, 7 diagnosis of COVID-19, 8 community acquired pneumonia, 9 the second-order perturbation delay Lane–Emden model in astrophysics, 10 the fifth type of induction motor model, 11 etc. Even though such problems can be well expressed by LSGO models, they will face a great challenge when solving their optima due to complex variables interaction or hard constraints.…”