A Neurophysiological Test for Psychiatric Diagnosis: Results in 750 Patients

Shagass, Charles; Jones, Arthur L.

doi:10.1176/ajp.114.11.1002

Cited by 69 publications

(12 citation statements)

References 5 publications

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“…Experiments carried out in the early days of the seda tion threshold model seem to support Eysenck's hypoth esis that dysthymics, because of their greater intro version, should have higher sedation thresholds than hys terics [Claridge, 1967;Claridge and Herrington, 1960;Shagass and Jones, 1958], It does not, of course, neces sarily follow that these results could be generalized to all introverts and to all extraverts.…”

Section: Sedation Thresholdmentioning

confidence: 81%

Drugs as Research Tools in Psychology: Experiments with Drugs in Personality Research

Eysenck¹

1983

Neuropsychobiology

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It is suggested that psychotropic drugs act to shift a person’s behaviour on the three major dimensions of personality in one direction or another, in predictable ways, and that it is possible to create a taxonomy of psychotropic drugs according to these effects. The history of this concept is traced and many examples given to illustrate how drug action and personality theory interact, and how this interaction can be used to gain greater insight into both personality and drug action.

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Section: Sedation Thresholdmentioning

confidence: 81%

Drugs as Research Tools in Psychology: Experiments with Drugs in Personality Research

Eysenck¹

1983

Neuropsychobiology

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“…This test was developed by Shagass (Shagass, 1954;Naiman, 1955, 1956;Shagass and Jones, 1958), the sedation threshold being the amount of sodium amytal required to produce a certain inflexion point determined with the aid of an E.E.G. tracing.…”

Section: Sedation Threshold Testmentioning

confidence: 99%

Parameters of Research into the Depressive States

Kessell

1968

Aust N Z J Psychiatry

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SYNOPSISCertain parameters of the depressive states are discussed, genetic, biochemical, physiological and psychological, and the literature is reviewed. It is considered that future drug evaluation studies require a multidisciplinary approach and the measurement of these parameters if we are to progress beyond the present confusion on the indications for the treatment of depression. Such an approach would also be expected to extend our knowledge of the pathophysiology of the depressive states. This review also emphasises those areas of special interest in depression.

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“…Sedation thresholds were found to be positively and significantly related to ratings of tension (Shagass, 1954) and manifest anxiety Naiman, 1955, 1956) in psychiatric patients, but negatively related to patients' ages (Shagass and Jones, 1958).…”

Section: Introductionmentioning

confidence: 97%

“…Of equal clinical interest were the findings that sedation thresholds related to the personality characteristics of hysteria and dysthmia (Claridge, 1967) and to the differential diagnosis of depressive illness (Shagass and Jones, 1958). Sedation thresholds, or indices of barbiturate tolerance which were high relative to normals were found to be characteristics of neurotic depressive illness.…”

Section: Introductionmentioning

confidence: 99%

The Galvanic Skin Response Inhibition Threshold: A Preliminary Study with an Australian Sample

Byrne¹,

Tottman²

1974

Aust N Z J Psychiatry

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SYNOPSWGalvanic skin response (G.S.R) inhibition thresholds, giving an index of barbiturate tolerance, were determined for 20 depressive and 10 normal subjects. Barbiturate tolerance was found to effectively differentiate neurotic from psychotic depressives, and b d h these groups from normal cootrols. Neurotic depressives generally exhibited high GS.R. inhibition thresholds relative to normals, while psychotic depressives exhibited low thresholds relative to normals. These results are discussed in t e r n of previous research on the sedation threshold.The G.S.R. inhibition threshold was found in some groups, to be systematically influenced by manifest anxiety. However, neither depressive severity nor age influenced barbiturate tolerance. Some potential clinical and experimental uses of the G.S.R inhibition threshold are discussed.

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A Neurophysiological Test for Psychiatric Diagnosis: Results in 750 Patients

Cited by 69 publications

References 5 publications

Drugs as Research Tools in Psychology: Experiments with Drugs in Personality Research

Drugs as Research Tools in Psychology: Experiments with Drugs in Personality Research

Parameters of Research into the Depressive States

The Galvanic Skin Response Inhibition Threshold: A Preliminary Study with an Australian Sample

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