This paper presents a commutation torque ripple suppression strategy for brushless DC motor (BLDCM) in the high-speed region, which considers the back electromotive force (back-EMF) variation during the commutation process. In the paper, the influence of actual back-EMF variation on the torque and outgoing phase current during the commutation process is analyzed. A modified smooth torque mechanism is then reconstructed considering the back-EMF variation, based on which a novel torque ripple suppression strategy is further designed. Compared with the traditional strategy which controls the chopping duty cycle relatively smoothly in the commutation process, the proposed strategy dynamically regulates the chopping duty cycle, which makes it show a gradual decrease. This strategy can suppress the commutation torque ripple even in a long commutation process, and broaden the speed range of the commutation torque ripple reduction. Under the experimental conditions of this paper, the proposed strategy can effectively reduce the commutation torque ripple in the high-speed region, and avoid the outgoing phase current cannot be reduced to zero. The experimental results verify the correctness of the theoretical analysis and the feasibility of the proposed strategy.