This paper studies the relationship between B2B e-commerce transaction volume and GDP by using cointegration relation test and Engel-Granger test methods. The result shows that long-term stable co-integration relationship did not exist: B2B causes the growth of GDP, but GDP is not the reason for the increase in B2B transactions. Meanwhile, this article also aimed to study the influence of B2B e-commerce information retrieval and communication, and extracted different B2B e-commerce mode of information retrieval and communication mode to improve the efficiency of information retrieval and communication, making the business flow, logistics, and cash flow more smooth.