A new aptamer/graphene interdigitated gold electrode piezoelectric sensor for rapid and specific detection of Staphylococcus aureus

Lian, Yan; He, Fengjiao; Wang, Huan; Tong, Feifei

doi:10.1016/j.bios.2014.10.017

Cited by 215 publications

(71 citation statements)

References 36 publications

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“…Compared with optical-based biosensors, electrochemical methods, in general, show the potential for construction of fast, simple, low-cost, sensitive, and high-throughput biosensors that can be miniaturized [81][82][83][84]. To date, electrochemical aptasensors are widely used for identification and quantification of pathogens.…”

Section: Electrochemical Strategiesmentioning

confidence: 99%

Current and Emerging Technologies for Rapid Detection of Pathogens

Zeng¹,

Wang²,

Hu³

2018

Biosensing Technologies for the Detection of Pathogens - A Prospective Way for Rapid Analysis

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Foodborne diseases, caused by pathogenic bacteria, have become an important social issue in the field of food safety. It presents a widespread and growing threat to human health in both developed and developing countries. As such, techniques for the detection of foodborne pathogens and waterborne pathogens are urgently needed to prevent the occurrence of human foodborne infections. Although traditional culture-based bacterial isolation and identification are the "gold standard" methods with high preciseness, their drawbacks in time-consuming are inadequate for rapid detection of pathogen to reduce foodborne disease occurrence. Fortunately, with the development of biotechnologies and nanotechnologies, various kinds of new technologies for rapid detection of pathogens have been developed so far, such as nucleic acid-based methods, antibody-based methods, and aptamer-based assays. In this chapter, we summarized the principles and the application of some recent rapid detection technologies for pathogenic bacteria. Moreover, the advantages and disadvantages of the established and emerging rapid detection methods are addressed here.

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Section: Electrochemical Strategiesmentioning

confidence: 99%

Current and Emerging Technologies for Rapid Detection of Pathogens

Zeng¹,

Wang²,

Hu³

2018

Biosensing Technologies for the Detection of Pathogens - A Prospective Way for Rapid Analysis

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“…After the groundbreaking experiments on the two-dimensional material graphene by Nobel Laureates, Sir Andre Geim and Konstantin Novoselov [16] from the University of Manchester, graphene came into limelight in research field mainly because of its excellent electrical [18], thermal [19], and mechanical properties [20]. Graphene found widespread applications in electronics [21], bio-electric sensors [22], energy technology [23], lithium batteries [24], aerospace [25], bio-engineering [26], and various other fields of nanotechnology [27]. In 2014, 2009 research papers were published on graphene in which about 830 papers were on graphene-epoxy nanocomposites produced using solution casting technique.…”

Section: Year Of Publicationsmentioning

confidence: 99%

“…The stiffness components can be written as given in Equation (44) where σ i is i th component of internal stress tensor, and i σ + and i σ − are stress tensors under tension and compression, respectively, and elastic properties of the system can be calculated using Equations (45)- (47) [43]. By using the MD simulation, the average stress in the system can be calculated using Equation (48) where σ 11 , σ 22 , and σ 33 are the virial stresses in x, y, and z directions, respectively, and σ is the average stress of the unit cell [43]. The stress-strain response can be evaluated by applying strain to the system repeatedly followed by MD equilibration.…”

Section: Constitutive Responsementioning

confidence: 99%

Modeling and Simulation of Graphene Based Polymer Nanocomposites: Advances in the Last Decade

Atif¹,

Inam²

2016

Graphene

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Modeling and simulation allow methodical variation of material properties beyond the capacity of experimental methods. The polymers are one of the most commonly used matrices of choice for composites and have found applications in numerous fields. The stiff and fragile structure of monolithic polymers leads to the innate cracks to cause fracture and therefore the engineering applications of monolithic polymers, requiring robust damage tolerance and high fracture toughness, are not ubiquitous. In addition, when "many-parts" cling together to form polymers, a labyrinth of molecules results, which does not offer to electrons and phonons a smooth and continuous passageway. Therefore, the monolithic polymers are bad conductors of heat and electricity. However, it is well established that when polymers are embedded with suitable entities especially nano-fillers, such as metallic oxides, clays, carbon nanotubes, and other carbonaceous materials, their performance is propitiously improved. Among various additives, graphene has recently been employed as nano-filler to enhance mechanical, thermal, electrical, and functional properties of polymers. In this review, advances in the modeling and simulation of grapheme based polymer nanocomposites will be discussed in terms of graphene structure, topographical features, interfacial interactions, dispersion state, aspect ratio, weight fraction, and trade-off between variables and overall performance.

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“…Aptamers bind to their pre-selected targets, including small substances, proteins and even whole cells with high specificity and affinity (Wu et al 2015;Zhao et al 2015b). Compared to antibodies, aptamers exhibit unique properties such as lack of immunogenicity and toxicity, low cost, excellent thermal stability and ease of synthesis and modification (Eissa et al 2015;Lian et al 2015;Luo et al 2014;Zhao et al 2015a). Aptamer-based sensors (aptasensors) have received substantial attention because of these properties .…”

Section: Introductionmentioning

confidence: 98%