A new automatic method for tracking rats in the Morris water maze

Forero, Manuel G.; Hernández, Natalia C.; Morera, Cristian M.; Aguilar, Luis Alonso Dr. Co-ASESOR Valdés; Aquino, Ruth; Baquedano, Laura E.

doi:10.1016/j.heliyon.2023.e18367

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2024

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Cited by 6 publications

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“…The Morris water maze (MWM) is the classic and most frequently used test for studying spatial learning and memory in rodents 1,2 . To date, several types of water mazes have been developed based on the classic MWM test, one of which is the acoustic-cued water maze 3 .…”

Section: Introductionmentioning

confidence: 99%

Sound intensities between 40 dB and 50 dB are suitable for acoustic-cued water maze tests

Han,

Fu,

Jiang

et al. 2024

Preprint

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We carried out an acoustic-cued water maze experiment at three sound intensity levels (30 dB, 40 dB, and 50 dB) in 30 mice (10 per group), aiming to determine the sound intensity suitable for an acoustic-cued water maze. The results showed that sound intensities at both 40 dB and 50 dB were effective in terms of the escape latency, the first crossing, the crossing number, and the quadrant time, and the effectiveness of both were about the same. On the other hand, a sound intensity of 30 dB was not as effective because there was no statistically significant improvement in escape latency across training days. Therefore, we consider sound intensities between 40 dB and 50 dB to be suitable for acoustic-cued water maze tests.

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Section: Introductionmentioning

confidence: 99%