A new benzofuran derivative from the leaves of <i>Ficus pumila</i> L.

Trinh, Pham Thi Nhat; An, Nguyen Huu; An, Pham Ngoc; Tri, Mai Dinh; Du, Cao Van; Minh, Phan Ngoc; Thuy, Nguyen Thi Le; Tuan, Nguyen Trong; Thoa, Vang Thi Kim; Tuấn, Nguyễn Ngọc; Dung, Le Tien

doi:10.1080/14786419.2017.1395427

Cited by 10 publications

(3 citation statements)

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“…The results from animal and in vitro studies suggest that the hypoglycemic actions of R. tuberosa could also be associated with the inhibition of α-amylase activity [61] and/or α-glucosidase activity [71]. Thus, preparations from this plant may be useful for controlling postprandial hyperglycemia by preventing the digestion of carbohydrates and delaying the increase in blood glucose [72].…”

Section: Plants With Hypoglycemic Properties Associated With Suriname...mentioning

confidence: 99%

“…Thus, preparations from this plant may be useful for controlling postprandial hyperglycemia by preventing the digestion of carbohydrates and delaying the increase in blood glucose [72]. Compounds in R. tuberosa that may be responsible for its α-amylase and α-glucosidase inhibitory activity are the pentacyclic triterpenoid betulin [61] and certain phenolic compounds including several flavonoids [67,71,73], respectively. This is consistent with the identification in the plant of triterpenoids and flavonoids [67], the hypoglycemic effects of these substances [59], and the implication of antioxidant activities in their blood glucoselowering capacity [68,69].…”

Section: Plants With Hypoglycemic Properties Associated With Suriname...mentioning

confidence: 99%

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Hypoglycemic Activity of Plant-Derived Traditional Preparations Associated with Surinamese from African, Hindustani, Javanese, and Chinese Origin: Potential Efficacy in the Management of Diabetes Mellitus

Mans¹

2022

Basics of Hypoglycemia

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Diabetes represents one of the most frequent causes of morbidity and mortality in the world. Despite the availability of a wide range of efficacious forms of treatment, many patients use traditional (plant-derived) preparations for treating their disease. The Republic of Suriname (South America) has a relatively high prevalence of diabetes. Due to its colonial history, the Surinamese population comprises descendants of all continents, the largest groups being those from enslaved Africans and from indentured laborers from India (called Hindustanis), Indonesia (called Javanese), as well as China. All these groups have preserved their cultural customs including their ethnopharmacological traditions, and are inclined to treat their diseases with plant-based preparations, either alone or together with allopathic medications. This chapter opens with some generalities about diabetes; subsequently provides some information about the history, worldwide epidemiology, diagnosis, types, and treatment of this disorder; then focuses on Suriname, giving some information about its geography, demographics, and economy, as well as the epidemiology of diabetes in the country; then extensively evaluates eight blood-glucose-lowering plants that are mainly associated with the four largest ethnic groups in Suriname by reviewing phytochemical, mechanistic, preclinical, and clinical literature data; and concludes with a consideration of the potential clinical usefulness of the plants against diabetes.

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Section: Plants With Hypoglycemic Properties Associated With Suriname...mentioning

confidence: 99%

Section: Plants With Hypoglycemic Properties Associated With Suriname...mentioning

confidence: 99%

Hypoglycemic Activity of Plant-Derived Traditional Preparations Associated with Surinamese from African, Hindustani, Javanese, and Chinese Origin: Potential Efficacy in the Management of Diabetes Mellitus

Mans¹

2022

Basics of Hypoglycemia

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“…Các thử nghiệm hoạt tính sinh học trên cao chiết và trên nhiều hợp chất phân lập được cho thấy khả năng kháng vi sinh vật, kháng oxy hoá, kháng viêm và ức chế sự phát triển của tế bào ung thư [6][7][8][9][10][11] . Cho đến nay, ở Việt Nam có rất ít công trình nghiên cứu về thành phần hoá học cũng như hoạt tính sinh học của loài thảo dược quý này 12,13 . Bài báo này công bố kết quả ly trích, phân lập và xác định cấu trúc của các hợp chất terpenoid từ cây sung thằn lằn, thu hái ở tỉnh Lâm Đồng.…”

Section: Giới Thiệuunclassified

Some terpenoids from Ficus pumila

Dieu Nguyen,

Nguyen

2021

Sci. Tech. Dev. J. - Nat. Sci.

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Ficus pumila L. is a species of the plant family Moraceae, distributed mainly in the tropical and subtropical Asia. It is a creeping shrub, growing on walls, rocks, tree trunks, and is cultivated for shade or ornamental purposes. All the plant organs are used in folk medicine for the treatment of diseases such as pain, rheumatism, hematuria, chronic dysentery, hemorrhoids and osteoporosis. Terpenoids, flavonoids, steroids, phenolic acids and coumarins are main classes of compounds found in this species, and exhibit antibacterial, antifungal, antioxidant, anti-inflammatory and inhibit the growth of several cancer cell lines. In Vietnam, there have been not many reports on the chemical constituents of F. pumila. In this study, we report the results of isolation and structure determination of four compounds from the stems and roots of this species collected in Lam Dong Province. Extraction was carried out using a Soxhlet extractor with ethyl acetate as the solvent. Recovery of the solvent produced an ethyl acetate extract. Compound isolation was performed using column chromatography on silica gel. Chemical structures were determined by analysis of the NMR spectra and comparison of the spectral data with relevant literature values. Four terpenoids comprising two dinorsesquiterpenoids, (6S,9R)-vomifoliol (1) and (6S)-dehydrovomifoliol (2), a sesquiterpenoid, phaseic acid (3), and a triterpenoid, methyl (2α,3β)-2,3-dihydroxy-olean-12-en-28-oate (4), were isolated from the ethyl acetate extract. Among the compounds, 3 and 4 are reported here for the first time from this species.

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