A New Cardiac Autonomic Function Predictor (Heart Rate Turbulence) in Patients with Ankylosing Spondylitis

Onrat, Ersel; Demirdal, Secil; Dursun, Hüseyin; Çakır, Tuğrul; Kılıt, Celal; Avsar, Alaettin; Kavuncu, Vural

doi:10.5152/tjr.2010.28

Cited by 3 publications

(3 citation statements)

References 32 publications

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“…Autonomic dysfunction, a condition first described by Toussirot in 1999 in AS patients, is well documented in literature. [5][6][7][8][9] The prevalence of autonomic neuropathy has been reported to vary from 24-…”

Section: Resultsmentioning

confidence: 99%

TNF-alpha blockade may improve autonomic dysfunction in ankylosing spondylitis

Krishan

Syngle

2014

IJRCI

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Section: Resultsmentioning

confidence: 99%

TNF-alpha blockade may improve autonomic dysfunction in ankylosing spondylitis

Krishan

Syngle

2014

IJRCI

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“…Abnormal increased activity has been shown in AS patients both in our study and previous studies. [29][30][31][32] It is predicted that these patients may have high risk for the development of AF. Though there is still no clear evidence, we believe that increased incidence of AF in AS patients may be related to chronic inflammation and increased myocardial fibrosis.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of Atrial Conduction Times, Epicardial Fat Thickness and Carotid Intima-Media Thickness in Patients With Ankylosing Spondylitis

et al. 2016

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Objectives: This study aims to determine the relationship between atrial electromechanical delay (EMD), carotid intima-media thickness (CIMT), and epicardial fat thickness (EFT) in ankylosing spondylitis (AS), which has a complicated inflammatory nature. Patients and methods:The study population included 42 consecutive patients with AS (28 males, 14 females; mean age 39.3±8.5 years; range 22 to 60 years) and 40 healthy subjects as controls (24 males, 16 females; mean age 37.2±8.7 years; range 22 to 60 years) (p>0.05). All patients underwent a standard tissue Doppler echocardiography to assess the left ventricular diastolic dysfunction, atrial EMD, CIMT, and EFT. All values were compared between the groups. Results: Interatrial (29.5±5.8 ms vs. 17.9±5.3 ms) left and right intraatrial EMD (18.2±4.6 ms and 11.7±3.5 ms vs. 11.9±3.2 ms and 7.1±3.2 ms, respectively) intervals were longer in AS patients than in healthy controls (all p<0.001). Left and right CIMT (0.50±0.11 mm and 0.44±0.06 mm vs. 0.51±0.11 mm and 0.43±0.04 mm, respectively) and EFT (0.73±0.15 cm and 0.63±0.07 cm) values were higher in AS patients than in healthy controls (all p<0.01). Conclusion: To our best knowledge, this is the first report evaluating the atrial EMD, CIMT, and EFT values together in AS patients. As indicators of cardiovascular involvement, all parameters were higher in AS patients.

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“…In Candemir et al's study, 19 AS patients were receiving anti-TNF therapy, which may have influenced their results. In previous study of Onrat et al, which evaluated 37 patients with AS, there was no significant difference between TO and TS [4]. This difference may be related to the low number of samples in the study of Onrat, or it may be related to the treatment they use.…”

mentioning

confidence: 81%