A new cluster of chikungunya virus West Africa genotype isolated from Aedes albopictus in China

Li, Nan; Peng, Chengcheng; Yuan, Yunfei; Hao, Yujia; Ma, Wenxue; Xiao, Pengpeng

doi:10.1016/j.jinf.2023.06.008

Cited by 2 publications

(1 citation statement)

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“…However, most of the outbreaks in West Africa were due to the WA genotype (8). More recently, evidence of distribution area of this genotype has been reported with the virus detection in mosquitoes in China (9). At the time of writing, the Western African region is facing a great CHIKV outbreak with the highest numbers of cases ever reported in Senegal (10,11) and Burkina Faso (12).…”

Section: Introductionmentioning

confidence: 99%

An amplicon-based Illumina and nanopore sequencing workflow for Chikungunya virus West Africa genotype

Dieng,

Ndiaye,

Kane

et al. 2023

Preprint

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The Chikungunya virus, a global arbovirus, is currently causing a major outbreak in the Western African region, with the highest cases reported in Senegal and Burkina Faso. Recent molecular evolution analyses reveal that the strain responsible for the epidemic belongs to the West African genotype, with new mutations potentially impacting viral replication, antigenicity, and host adaptation. Real-time genomic monitoring is needed to track the virus’s spread in new regions. A scalable West African genotype amplicon-based Whole Genome Sequencing for multiple Next Generation Sequencing platforms has been developed to support genomic investigations and identify epidemiological links during the virus’s ongoing spread. This technology will help identify potential threats and support real-time genomic investigations in the ongoing spread of the virus.

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Section: Introductionmentioning

confidence: 99%